周细胞是具伸缩性的类似平滑肌细胞的一类细胞,它们覆盖在微脉管的基底面。周细胞是小静脉的主要成分,并普遍存在于毛细血管中。在不同的组织和器官中,周细胞的数量和功能呈现很大的差异。周细胞的三种主要功能是(1)参与中枢神经系统微血管收缩性,(2)内皮细胞活性及(3)巨噬细胞活性的调节。也有证据表明周细胞与血脑屏障的物质转运及血管渗透性的调节有关。病理学研究显示,周细胞与高血压、糖尿病视网膜病变、阿尔海默氏病、多发性硬化和中枢神经系统肿瘤的形成有关。
货号 | 1200 |
产地 | 美国 |
缩写 |
HBVP |
规格 | 5 x 10^5 cells/vial |
用途 | 科研 |
运输 | 干冰 |
保存 |
液氮 |
9.) Bai, Y., Zhu, X., Chao, J., Zhang, Y., Qian, C., Li, P., Liu, D., Han, B., Zhao, L., Zhang, J., Buch, S., Teng, G., Hu, G. & Yao, H. (2015) Pericytes Contribute to the Disruption of the Cerebral Endothelial Barrier via Increasing VEGF Expression: Implications for Stroke PLoS One. 10
Do you have an STR profile available for Human Brain Vascular Pericytes #1200?
Hi Daniel,
We apologize for the inconvenience, but the STR profile for Catalog #1200 is not currently available. Please email your request to TechSupport@sciencellonline.com and we will respond as soon as possible.”
Best,
Sciencell Team
Are they GFAP positive?
Hi duan,
Human Brain Vascular Pericytes are NOT GFAP positive.
Thank you
How are these cells isolated? Are they PDGFRb+? Do you know if they express other pericyte markers like NG2?
Dear customer,
Isolation method is proprietary. #1200 cells express both PDGF beta receptor and NG2.
Do you know the ApoE genotype information of these human pericytes? ApoE2, ApoE3 or ApoE4. Can request a specific one?
Hi,
We do not test these. thanks for your interest, please email at techsupport@sciencellonline,.com for special services.
SCIENCELL TEAM
The spec sheet says you can passage these cells 15 times, but I don't see it listed anywhere that they are immortalized. Please clarify.
Hi Susan,
The cells can proliferate for 15 population doublings, not 15 passages. Cells may reach 15 population doublings within 4-5 passages. thanks for your interest
SCIENCELL