产品名称	A498人肾癌细胞
货号	ZQ0467
产品介绍	A498是一种人肾癌细胞系，最初由Aaronson S建立，源自一位52岁患有肾癌的女性病人的肾组织。被广泛用于与肾癌相关的研究，特别是研究透明细胞肾细胞癌，这是成人中最常见的肾癌类型。该细胞系具有上皮样形态，是研究肾癌发生的分子和细胞机制的重要模型。其表现出肾癌的几个典型特征，包括参与细胞周期调节、细胞凋亡和血管生成的基因表达的改变。对于检查肾癌改变的代谢途径特别有用，因为它们显示了一个独特的代谢轮廓，包括脂质和葡萄糖代谢的变化。这方面使它们适合于代谢靶向研究，探索改变代谢途径如何抑制肿瘤生长。此外，A498细胞被用于药物发现和毒理学研究，以测试新的化疗药物和靶向治疗的疗效。它也被用于研究肾癌细胞对缺氧条件的反应——这是实体肿瘤的一个共同特征，显著影响肿瘤行为和治疗反应。总之，A498细胞系作为肾癌研究的重要工具，促进了更有效治疗策略的发展，增强了我们对肾癌生物学的理解。
种属	人
性别/年龄	女/52岁
组织	肾脏
疾病	肾癌
细胞类型	肿瘤细胞
形态学	上皮的
生长方式	贴壁
倍增时间	大约33~66.8小时
培养基和添加剂	MEM（含NEAA）基础培养基（中乔新舟   货号：ZQ-300）+10%FBS（中乔新舟  货号：ZQ0500）+1%双抗（中乔新舟  货号：CSP006）
推荐完全培养基货号	ZM0467
生物安全等级	BSL-1
STR位点信息	Amelogenin：x,x CSF1PO：11,12 D12S391：21,21 D13S317：12,12 D16S539：12,12 D18S51：17,17 D19S433：12,12 D21S11：28,32 D2S1338：26,26 D3S1358：15,15 D5S818：11,13 D6S1043：11,11 D7S820：10,11 D8S1179：13,15 FGA：18,20 Penta E：10,14 TH01：6,9.3 TPOX：8,11 vWA：18,18
培养条件	95%空气，5%二氧化碳；37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC; CRL-7908 ATCC; HTB-44 DSMZ; ACC-55
供应限制	仅供科研使用

货号	ZQ0467
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

论文标题： Chiral NIR-II fluorescent Ag2S quantum dots with stereospecific biological interactions and tumor accumulation behaviors
DOI： 10.1016/j.scib.2022.05.001
发表时间： 2022-05-04
期刊： Science Bulletin
影响因子： 11.78
货号： ZQ0336/ZQ0467/ZQ0481
产品名称： Human renal carcinoma cell line RCC cells

原文链接： https://www.sciencedirect.com/science/article/pii/S2095927322001955

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