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OCI-Aml-3人急性髓性白血病细胞 (STR鉴定)

英文名:OCI-Aml-3
货号:ZQ0580
价格:¥1800.00
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推荐组合

OCI-Aml-3人急性髓性白血病细胞 (STR鉴定)

¥1800.00
+

OCI-Aml-3急性淋巴细胞专用培养基

¥650.00

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细胞套餐惊爆价

¥2450
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

OCI-Aml-3人急性髓性白血病细胞

货号

ZQ0580

产品介绍

OCI-Aml-3是一种人急性髓性白血病细胞系,是从1987年诊断为急性髓细胞性白血病(AML FAB M4)的57岁男性的外周血中建立的。细胞携带NPM1基因突变(A型)和DNMT3A R882C突变。广泛用于急性髓性白血病的研究,包括药物筛选、细胞信号传导研究、白血病的分子机制研究等。例如:OCI-Aml-3细胞系在药物筛选中的应用主要包括以下几个方面:白血病药物靶点的鉴定、药物敏感性测试、药物组合效应研究、药物耐药性研究、药物开发和前临床研究、药物作用机制研究等。这些应用展示了OCI-Aml-3细胞系在AML药物筛选和研究中的广泛价值,为开发新的治疗策略和药物提供了重要的实验工具。

种属

性别/年龄

男/57岁 

组织

外周血

疾病

急性髓性白血病

细胞类型

肿瘤细胞 

形态学

单个,主要是圆形细胞

生长方式

悬浮

倍增时间

大约28~40小时

培养基和添加剂

RPMI-1640基础培养基(中乔新舟 货号:ZQ-200+20%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0580

生物安全等级

BSL-1

STR位点信息

Amelogenin:X;
CSF1PO: 11,12;
D2S1338:17,21;
D3S1358:16;
D5S818: 11,13;
D7S820: 9,10;
D8S1179:10,12;
D13S317:8,13;
D16S539:11,13;
D18S51: 12,18;
D19S433:15,17;
D21S11: 29,30;
FGA:22;
Penta D: 12,13;
Penta E: 11,13;
TH01: 8,9.3 (DSMZ=ACC-582);
             8,10 (Cosmic-CLP=1290455; PubMed=25877200);
TPOX:8,11;
vWA:17,18;

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

DSMZ; ACC-582

供应限制

仅供科研使用

货号

ZQ0580

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


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