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CAL 27人舌鳞状细胞癌细胞(STR鉴定)

英文名:CAL 27
货号:ZQ0606
价格:¥1350.00
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CAL 27人舌鳞状细胞癌细胞(STR鉴定)

¥1350.00
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CAL 27人舌鳞状细胞癌细胞专用培养基

¥350.00 ¥480.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥1700 ¥2080.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

CAL 27人舌鳞状细胞癌细胞

货号

ZQ0606

产品介绍

CAL 27是一种人舌鳞状细胞癌细胞系,源自1982年由J. Gioanni(法国尼斯塞德市安托万·拉卡塞格内中心)从一位56岁男性舌头上的原发肿瘤组织中建系,该患者患有舌中部病变。

细胞具有高密度颗粒状胞浆和上皮细胞样的形态,贴壁生长。具有高侵袭性和转移能力,对某些药物敏感,但对其他一些药物如VP16、CCNU、VM26、ADM、CPA和MTX表现出耐药性。被广泛用于科学研究,以研究口腔致癌作用、鳞状细胞和口咽癌的生物学,以及评估头颈癌的潜在治疗药物。

CAL 27细胞已在多种研究应用中得到使用,包括细胞增殖、凋亡的研究,特别是在抗癌药物敏感性和寻找新型抗癌药物的背景下,以及迁移和侵袭的研究。它们还被用于研究各种化疗药物如顺铂、放射疗法和靶向疗法的效果。
CAL-27腺鳞状细胞癌系进一步被用作异种移植瘤,这对于研究肿瘤血管生成、淋巴结转移以及转移和化疗抗性机制非常有用。CAL27细胞与整合素α6β4和αvβ3的相互作用引起了人们的兴趣,因为这些分子在细胞粘附中起着至关重要的作用。已有研究探索了使用vismodegib和itraconazole等药物靶向这些途径的效果,这些物质已知能够调节Hedgehog信号通路。
总体而言,CAL 27细胞系作为一个强大的模型,用于研究口腔鳞状细胞癌的复杂生物学,并测试新的治疗干预措施,从而促进了口腔癌管理和治疗的进步。

种属

性别/年龄

男/56岁

组织

舌头

疾病

鳞状细胞癌

细胞类型

肿瘤细胞

形态学

上皮的

生长方式

贴壁

倍增时间

大约20~45小时 

培养基和添加剂

MEM(含NEAA)(中乔新舟  货号:ZQ-300)+10%胎牛血清(中乔新舟  货号:ZQ500-A)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0606

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

D3S1358: 16
TH01: 6,9.3
D21S11: 28,29
D18S51: 13
Penta_E: 7
D5S818: 11,12
D13S317: 10,11
D7S820: 10
D16S539: 11,12
CSF1PO: 10,12
Penta_D: 9,10
vWA: 14,17
D8S1179: 13,15
TPOX: 8
FGA: 25
D19S433: 14,15.2
D2S1338: 23,24

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC; CRL-2095 BCRJ; 0326 DSMZ; ACC-446

供应限制

仅供科研使用

货号

ZQ0606

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: YKT6, as a potential predictor of prognosis and immunotherapy response for oral squamous cell carcinoma, is related to cell invasion, metastasis, and CD8+ T cell infiltration
DOI: 10.1080/2162402X.2021.1938890
发表时间: 2021-06-23
期刊: OncoImmunology
影响因子: 8.11
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/2162402X.2021.1938890


论文标题: Genetic variants associated with expression of TCF19 contribute to the risk of head and neck cancer in Chinese population
DOI: 10.1136/jmedgenet-2020-107410
发表时间: 2022-04-01
期刊: JOURNAL OF MEDICAL GENETICS
影响因子: 5.941
货号: ZQ0606
产品名称: CAL27 cells

原文链接: https://jmg.bmj.com/content/59/4/335.abstract


论文标题: Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway
DOI: 10.1111/cas.14362
发表时间: 2020-03-18
期刊: CANCER SCIENCE
影响因子: 4.966
货号: ZQ0606
产品名称: CAL27 OSCC cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7226219/


论文标题: ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2
DOI: 10.7150/jca.63919
发表时间: 2021-10-25
期刊: Journal of Cancer
影响因子: 4.207
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8734408/


论文标题: Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells
DOI: 10.2147/OTT.S174637
发表时间: 2018-11-13
期刊: OncoTargets and Therapy
影响因子: 4.147
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239101/


论文标题: MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells
DOI: 10.1155/2021/6650791
发表时间: 2021-06-04
期刊: Biomed Research International
影响因子: 3.411
货号: ZQ0606
产品名称: CAL 27 cells
原文链接: https://www.hindawi.com/journals/bmri/2021/6650791/


论文标题: Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway
DOI: 10.1155/2021/6616547
发表时间: 2021-06-10
期刊: Biomed Research International
影响因子: 3.411
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.hindawi.com/journals/bmri/2021/6616547/


论文标题: Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter
DOI: 10.1080/21655979.2021.2012951
发表时间: 2021-12-29
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.2012951


论文标题: Zinc‑finger protein 750 mitigates malignant biological behavior of oral CSC‑like cells enriched from parental CAL‑27 cells
DOI: 10.3892/ol.2021.13146
发表时间: 2021-11-19
期刊: Oncology Letters
影响因子: 2.967
货号: ZQ0606
产品名称: CAL-27 cells

原文链接: https://www.spandidos-publications.com/10.3892/ol.2021.13146



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Fanconi anemia-isogenic head and neck cancer cell line pairs: a basic and translational science resource.
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