产品名称 |
NCI-H929人骨髓瘤细胞株 |
货号 |
ZQ0618 |
产品介绍 |
NCI-H929 [H929]细胞是从62岁白人女性浆细胞瘤骨髓瘤患者的恶性积液中分离的B淋巴细胞。在癌症和免疫学研究中使用这些细胞。这些细胞在癌症研究中特别有用,因为它们能够大量产生免疫球蛋白,使它们成为研究多发性骨髓瘤生物学和免疫球蛋白产生机制的主要模型。NCI-H929细胞以悬浮培养方式生长。
在遗传学上,NCI-H929细胞表现出与多发性骨髓瘤常见的几种染色体异常,包括易位和扩增。这些遗传特征使它们成为研究骨髓瘤遗传基础和测试潜在治疗干预措施的宝贵资源。研究人员经常在药物筛选实验中使用NCI-H929细胞来评估新的抗骨髓瘤化合物的疗效,并了解耐药机制。它们在各种实验条件下一致且可重复的行为进一步增强了它们在临床前研究中的实用性。 |
种属 |
人 |
性别/年龄 |
女/62岁 |
组织 |
骨骼;骨髓 |
疾病 |
浆细胞骨髓瘤 |
细胞类型 |
肿瘤细胞 |
形态学 |
成淋巴细胞 |
生长方式 |
悬浮 |
倍增时间 |
大约50~70小时 |
培养基和添加剂 |
RPMI-1640(品牌:中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X CSF1PO: 11 D13S317: 12 D16S539: 9,13 D5S818: 11,12 D7S820: 10,12 THO1: 9.3 TPOX: 8,11 vWA: 14,15 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; CRL-9068 BCRC; 60386 DSMZ; ACC-163 ECACC; 95050415 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0618 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: Globular C1q Receptor (gC1qR/p32/HABP1) Suppresses the Tumor-Inhibiting Role of C1q and Promotes Tumor Proliferation in 1q21-Amplified Multiple Myeloma
DOI: 10.3389/fimmu.2020.01292
发表时间: 2020-07-14
期刊: Frontiers in Immunology
影响因子: 5.085
货号: ZQ0618
产品名称: H929 cells
原文链接: https://www.frontiersin.org/articles/10.3389/fimmu.2020.01292/full
论文标题: MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma
DOI: 10.1080/21655979.2021.1920325
发表时间: 2021-05-04
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0618
产品名称: NCI-H929 cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1920325
论文标题: Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo
DOI: 10.1016/j.bbrc.2018.09.140
发表时间: 2018-10-03
期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子: 2.559
货号: ZQ0618
产品名称: NCI-H929 cells
原文链接: https://www.sciencedirect.com/science/article/pii/S0006291X18320618
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货号 | 产品名称 | 规格 | 价格 | 指令 |