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Capan-2人胰腺癌细胞(STR鉴定)

英文名:Capan-2
货号:ZQ0923
价格:¥1350.00
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Capan-2人胰腺癌细胞(STR鉴定)

¥1350.00
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Capan-2人胰腺癌细胞专用培养基

¥350.00 ¥500.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥1700 ¥2300.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

Capan-2人胰腺癌细胞

货号

ZQ0923

产品介绍

Capan-2是一种人胰腺癌细胞系,起源于1975年从一位56岁白人男性胰腺癌患者的胰腺组织中分离出来。它源自肝脏的转移部位,表明其起源于继发性肿瘤,这使得它对于转移过程和胰腺癌生物学的研究特别有价值。这些细胞表现出上皮形态,并已广泛用于研究胰腺癌、耐药性和肿瘤生物学。这种细胞系具有多边形形态,属于假三倍体,其主要染色体数模态为69,但也存在范围在65至74之间的变异 。

Capan-2 细胞已知表达 Kirsten 大鼠肉瘤病毒癌基因同源物 (KRAS) 的突变形式,这是胰腺癌中的常见突变,这使它们成为研究 KRAS 驱动的肿瘤发生的强大模型。此外,它们的特征是肿瘤抑制基因 p53 突变的表达,并观察到表现出染色体不稳定性,这是与癌症进展和治疗反应相关的关键特征。该细胞系已用于许多研究,包括评估化疗效果、探索癌症进展的分子途径以及开发靶向治疗策略。

注意事项:

(1)capan-2 细胞呈块片状聚集生长,细胞胞体黑点较多是正常现象。
(2)细胞复苏需要5-7天可传代,传代后细胞需要48小时后才可换液操作,每两天换液一次。

种属

性别/年龄

男/56岁

组织

胰腺

疾病

腺癌

细胞类型

肿瘤细胞  

形态学

多边形上皮样, 贴壁生长

生长方式

贴壁

倍增时间

大约120~168小时  

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0923

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 11,12
D13S317: 11,12
D16S539: 9,13
D5S818: 11,12
D7S820: 9,11
TH01: 9.3
TPOX: 8
vWA: 17
D3S1358: 17,18
D21S11: 31
D18S51: 13
Penta_E: 11
Penta_D: 13,15
D8S1179: 12,13
FGA: 21,24
D19S433: 13,15
D2S1338: 19,25

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ATCC; HTB-80 BCRJ; 0060 

供应限制

仅供科研使用

货号

ZQ0923

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


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CLPUB00416

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