产品名称 |
glioma261小鼠神经胶质瘤细胞 |
货号 |
ZQ0932 |
产品介绍 |
20世纪90年代中期从Gl261肿瘤体外培养细胞,1939年通过颅内注射3-甲基胆蒽诱导C57BL/6小鼠,随后在同基因小鼠品系中连续移植维持细胞培养;文献中描述了携带TP53和KRAS突变的细胞。 |
种属 |
小鼠 |
组织来源 |
脑 |
形态学 |
上皮细胞样 |
细胞类型 |
肿瘤细胞 |
倍增时间 |
~100-120 hours (DSMZ=ACC-802). |
生长方式 |
贴壁 |
培养基和添加剂 |
|
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
保藏机构 |
BCRJ; 0299 DSMZ; ACC-802 NCI-DTP; Glioma 261 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0932 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
PubMed=16734735; DOI=10.1111/j.1349-7006.2006.00208.x
Szatmari T., Lumniczky K., Desaknai S., Trajcevski S., Hidvegi E.J., Hamada H., Safrany G.
Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy.
Cancer Sci. 97:546-553(2006)
PubMed=23248259; DOI=10.4049/jimmunol.1201557
Ohlfest J.R., Andersen B.M., Litterman A.J., Xia J.-Z., Pennell C.A., Swier L.E., Salazar A.M., Olin M.R.
Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model.
J. Immunol. 190:613-620(2013)
PubMed=23686484; DOI=10.4049/jimmunol.1203539
Litterman A.J., Zellmer D.M., Grinnen K.L., Hunt M.A., Dudek A.Z., Salazar A.M., Ohlfest J.R.
Profound impairment of adaptive immune responses by alkylating chemotherapy.
J. Immunol. 190:6259-6268(2013)
PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)
PubMed=30084848; DOI=10.1038/sdata.2018.157
Schuster H., Shao W.-G., Weiss T., Pedrioli P.G.A., Roth P., Weller M., Campbell D.S., Deutsch E.W., Moritz R.L., Planz O., Rammensee H.-G., Aebersold R., Caron E.
A tissue-based draft map of the murine MHC class I immunopeptidome.
Sci. Data 5:180157-180157(2018)
PubMed=30524896; DOI=10.1080/2162402X.2018.1501137
Genoud V., Marinari E., Nikolaev S.I., Castle J.C., Bukur V., Dietrich P.-Y., Okada H., Walker P.R.
Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models.
OncoImmunology 7:e1501137.1-e1501137.10(2018)