产品名称	PATU 8988T人胰腺癌细胞
货号	ZQ0730
产品介绍	PATU 8988T是一种人胰腺癌细胞系，该细胞系最初是1985年从一名64岁妇女的原发性胰腺癌肝转移中建立的。PATU8988T和PATU8988S (DSM ACC 204)是来自同一患者的胰腺细胞系。细胞呈上皮细胞样形态，具有贴壁生长的特性。是微卫星稳定型（MSS），并且携带KRAS和TP53基因突变。表达上皮细胞标志物，如E-cadherin，以及胰腺癌相关标志物，如CA19-9和CEA。 PATU 8988T细胞系在药物筛选中有以下应用：药物反应研究、药物敏感性测试、药物筛选模型、药物机制研究、药物再利用、化合物库筛选、AI药物研发、类器官技术：PATU 8988T细胞系也被用于类器官技术中，以模拟胰腺癌的微环境，进行更接近人体生理状态的药物测试。这些应用展示了PATU 8988T细胞系在胰腺癌药物研发中的广泛潜力。
种属	人
性别/年龄	女/64岁
组织	胰腺
疾病	胰腺癌
细胞类型	肿瘤细胞
形态学	上皮样
生长方式	贴壁
倍增时间	大约：4.7-5.2 days (PubMed=1348891); ~22-30 hours (DSMZ=ACC-162)
培养基和添加剂	DMEM (中乔新舟  货号：ZQ-100)+5%胎牛血清（中乔新舟 货号：ZQ500-A）+ 5%马血清（中乔新舟 货号：ZQH500）+1%P/S（中乔新舟  货号：CSP006）
推荐完全培养基货号	ZM0730
生物安全等级	BSL-1
培养条件	95%空气，5%二氧化碳；37℃
STR位点信息	Amelogenin： X CSF1PO ：11,13 D2S1338： 23 D3S1358 ：15,17 D5S818： 11,13 D7S820： 7,8 D8S1179： 13,16 D13S317： 12,13 D16S539： 11,12 D18S51 ：12 D19S433： 14,15 D21S11： 26 FGA： 23 Penta D ：8 Penta E： 14 TH01： 6 TPOX ：8,11 vWA： 16
抗原表达/受体表达	***
基因表达	***
保藏机构	DSMZ; ACC-162
供应限制	仅供科研使用

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