Description |
Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family of mitogenic peptides which is comprised of at least 22 proteins. FGF signaling factors play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. bFGF is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. bFGF signals through FGF receptor 1b, 1c, 2c, 3c and 4. |
Synonyms |
FGF-2, Fibroblast Growth Factor-basic |
AA Sequence |
PALPEDGGGA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKYSSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS |
Source |
Escherichia coli |
Molecular Weight |
Approximately 16.3 kDa, a single non-glycosylated polypeptide chain containing 145 amino acids. |
Biological Activity |
Fully biologically active. The ED50 is ? 0.2 ng/ml, corresponding to a specific activity of ? 5 x 10^6 units/mg, as determined by proliferation of BALB/c 3T3 cells |
Physical Appearance |
White lyophilized powder. |
Formulation |
Lyophilized from a 0.2μm filtered solution in PBS, pH 7.4. |
Endotoxin |
< 1EU/μg of growth factor as determined by LAL method. |
Reconstitution |
Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
Storage |
Store at -20°C after receiving. Upon Reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
Usage |
This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| 货号 | 144-02 |
| 产地 | 美国 |
| 缩写 |
rr bFGF |
| 规格 |
10µg |
| 用途 | 科研 |
| 包装 | 管装 |
| 保存 |
-20℃冰箱 |
上海中乔新舟生物科技有限公司
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