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A-673人横纹肌肉瘤细胞(STR鉴定)

英文名:A-673
货号:ZQ0107
价格:¥1400.00
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A-673人横纹肌肉瘤细胞(STR鉴定)

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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

A-673人横纹肌肉瘤细胞

货号

ZQ0107

产品介绍

A-673人横纹肌肉瘤细胞系是一种源自15岁女性患者的恶性肿瘤细胞系,最初被认为是横纹肌肉瘤,但后来的研究表明它具有Ewing肉瘤的特征。该细胞系在软琼脂上可以形成克隆,在免疫抑制血清处理的小鼠中成瘤,具有致瘤性。

种属

性别/年龄

女/15岁

组织

肌肉

疾病

尤因肉瘤(NCIt:C4817) 

生物安全等级

BSL-1

STR位点信息

Amelogenin: X
CSF1PO: 11,12
D13S317: 8,13
D16S539: 11
D5S818: 11,12
D7S820: 10,12
TH01: 9.3
TPOX: 8
vWA: 15,18
D3S1358: 14
D18S51: 13,16
Penta_E: 10,13
Penta_D: 12,13
D8S1179: 11,13
FGA: 19,20
D19S433: 13,14
D2S1338: 16,21
D21S11: 29,30.2
D18S51: 13,16 

细胞类型

肿瘤细胞

形态学

多边形

生长方式

贴壁细胞

倍增时间

大约24~28小时 

培养基和添加剂

90%DMEM高糖(品牌:中乔新舟 货号:ZQ-100)+10%FBS(品牌:中乔新舟 货号:ZQ500-A)+1%双抗(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0107 

培养条件

37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC;  ECACC

供应限制

仅供科研使用

货号

ZQ0107

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用



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A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)


6、PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074
Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J.
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)


7、PubMed=26428435; DOI=10.1016/j.ejca.2015.08.020
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CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients.
Eur. J. Cancer 51:2624-2633(2015)


8、PubMed=26589293; DOI=10.1186/s13073-015-0240-5
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TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)


9、PubMed=26979953; DOI=10.1073/pnas.1521251113
Town J., Pais H., Harrison S., Stead L.F., Bataille C., Bunjobpol W., Zhang J., Rabbitts T.H.
Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target.
Proc. Natl. Acad. Sci. U.S.A. 113:3603-3608(2016)


10、PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)


11、PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
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12、PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014
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Mol. Ther. 27:933-946(2019)


13、PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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14、PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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15、PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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16、DOI=10.5282/edoc.27750
Orth M.F.
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021), Ludwig Maximilians University of Munich, Germany


17、PubMed=34413129; DOI=10.1158/1535-7163.MCT-21-0089
Gartrell J., Mellado-Largarde M., Clay M.R., Bahrami A., Sahr N.A., Sykes A., Blankenship K., Hoffmann L., Xie J., Cho H.P., Twarog N., Connelly M., Yan K.-K., Yu J.-Y., Porter S.N., Pruett-Miller S.M., Neale G., Tinkle C.L., Federico S.M., Stewart E.A., Shelat A.A.
SLFN11 is widely expressed in pediatric sarcoma and induces variable sensitization to replicative stress caused by DNA-damaging agents.
Mol. Cancer Ther. 20:2151-2165(2021)


18、PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

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