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NCI-H1793非小细胞肺癌腺癌细胞

英文名:NCI-H1793
货号:ZQ1139
价格:¥5200.00
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NCI-H1793非小细胞肺癌腺癌细胞

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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

NCI-H1793非小细胞肺癌腺癌细胞

货号

ZQ1139

产品介绍

NCI-1793[H1793]是一种细胞系,表现为上皮形态,从一名52岁女性非小细胞肺癌患者的肺中分离出来:腺癌。本产品在癌症研究中有应用价值。非小细胞肺癌(NSCLC)是肺癌中最常见的类型,占所有肺癌的大约85%。它包括几种不同的病理类型,其中最常见的是肺腺癌(LUAD)和肺鳞状细胞癌(LUSC)。NSCLC的发病机制复杂,涉及多个分子途径和遗传因素及基因突变、肿瘤微环境、上皮-间质转化(EMT)、慢性炎症等。NCI-H1793它为研究非小细胞肺癌的发病机制提供了重要的实验模型。通过在体外培养NCI-H1793细胞,研究人员可以观察和研究肿瘤细胞的生物学特性,如增殖、侵袭、迁移和对药物的反应。此外,NCI-H1793细胞系也可用于测试新的抗癌药物和治疗方法,以及探索肿瘤微环境中细胞间的相互作用。

例如,最近的研究揭示了ZFP36和BARX1在非小细胞肺癌中的潜在作用。研究发现,ZFP36缺失导致BARX1表达上调,进而促进NSCLC细胞的增殖、迁移和侵袭。这些发现有助于更好地理解非小细胞肺癌的发病机制,并可能揭示新的治疗靶点。
综上所述,NCI-H1793细胞系通过模拟非小细胞肺癌的生物学行为,为研究其复杂的发病机制提供了宝贵的工具,有助于推动新的治疗方法的发展。

种属

性别/年龄

女/52岁

组织

疾病

肺腺癌

细胞类型

肿瘤细胞

形态学

上皮

生长方式

贴壁

培养基和添加剂

DMEM/F12基础培养基(中乔新舟  货号:ZQ-600)+10%胎牛血清(中乔新舟  货号:ZQ500-A+1%P/S(中乔新舟  货号:CSP006+10 nM beta-estradiol + 10 nM Hydrocortisone + 0.05 mg/mL Insulin + 0.01 mg/mL Transferrin + 30 nM Sodium selenite

推荐完全培养基货号

ZM1139

生物安全等级

BSL-1

培养条件

95%空气,5%二氧化碳;37℃

STR位点信息

Amelogenin: X
CSF1PO: 9,12
D13S317: 8,12
D16S539: 13
D5S818: 11,12
D7S820: 7,8
TH01: 9,9.3
TPOX: 8
vWA: 18
D3S1358: 17,18
D21S11: 28
D18S51: 10,11,18
Penta_E: 14,16
Penta_D: 13,14
D8S1179: 8,13
FGA: 23.2,24
D19S433: 13,14
D2S1338: 17

抗原表达/受体表达

***  

基因表达

***  

保藏机构

ATCC; CRL-5896  KCLB; 91793

供应限制

仅供科研使用

货号

ZQ1139

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用

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