产品名称 |
Daoy人髓母细胞瘤细胞 |
货号 |
ZQ0302 |
产品介绍 |
Daoy细胞系是由西澳大利亚皇家珀斯医院的P. F Jacobsen于1985年建立的。 是从患有促结缔组织增生性小脑髓母细胞瘤的4岁男性患者的小脑中分离出的多边形细胞。活检肿瘤取自后颅窝。Daoy Med细胞系可用于神经科学研究。是一种源自髓母细胞瘤的细胞系,髓母细胞瘤是一种主要见于儿童的脑肿瘤。髓母细胞瘤通常位于小脑,这是大脑中对运动控制和协调至关重要的区域,是儿童中最常见的恶性脑肿瘤。
|
种属 |
人 |
性别/年龄 |
男/4岁 |
组织 |
大脑/小脑 |
疾病 |
桥小脑髓母细胞瘤 |
细胞类型 |
肿瘤细胞 |
形态学 |
多边形 |
生长方式 |
贴壁 |
倍增时间 |
大约30.5~34小时 |
培养基和添加剂 |
DMEM (中乔新舟 货号:ZQ-100)+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X
CSF1PO: 11
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; HTB-186 BCRJ; 0325 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0302 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
PubMed=2993532; DOI=10.1097/00005072-198509000-00003
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Brain tumors.
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PubMed=12973738; DOI=10.1002/pmic.200300460
Peyrl A., Krapfenbauer K., Slavc I., Yang J.-W., Strobel T., Lubec G.
Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and principles.
Proteomics 3:1781-1800(2003)
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Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer stem-like phenotype.
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Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)
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Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.
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MDM2 antagonism by nutlin-3 induces death in human medulloblastoma cells.
Neurosci. Lett. 513:106-110(2012)
PubMed=22460905; DOI=10.1038/nature11003
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
PubMed=22723427; DOI=10.1093/neuonc/nos130
Sikkema A.H., den Dunnen W.F.A., Hulleman E., van Vuurden D.G., Garcia-Manero G., Yang H., Scherpen F.J.G., Kampen K.R., Hoving E.W., Kamps W.A., Diks S.H., Peppelenbosch M.P., de Bont E.S.J.M.
EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.
Neuro-oncol. 14:1125-1135(2012)
PubMed=24297863; DOI=10.1158/1078-0432.CCR-13-2281
Bandopadhayay P., Bergthold G., Nguyen B., Schubert S., Gholamin S., Tang Y.-J., Bolin S., Schumacher S.E., Zeid R., Masoud S., Yu F.-R., Vue N., Gibson W.J., Paolella B.R., Mitra S.S., Cheshier S.H., Qi J., Liu K.-W., Wechsler-Reya R.J., Weiss W.A., Swartling F.J., Kieran M.W., Bradner J.E., Beroukhim R., Cho Y.-J.
BET bromodomain inhibition of MYC-amplified medulloblastoma.
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PubMed=25877200; DOI=10.1038/nature14397
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A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)
PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
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A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)
PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)
PubMed=27812533; DOI=10.1016/j.dib.2016.10.004
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Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)
PubMed=29900115; DOI=10.1016/j.euprot.2016.03.015
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Top-down proteomic characterization of DAOY medulloblastoma tumor cell line.
EuPA Open Proteomics 12:13-21(2016)
PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ0048 | A172人胶质母细胞瘤细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1600.00 | 放入购物车 》 |
ZQ0050 | SH-SY5Y人神经母细胞瘤细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0051 | SK-N-AS人神经母细胞瘤细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1500.00 | 放入购物车 》 |
ZQ0054 | U-87 MG人脑星形胶质母细胞瘤(STR鉴定)[套餐促销] | 5 x 10^5 cells/vial | ¥1600.00 | 放入购物车 》 |
ZQ0398 | IMR-32人神经母细胞瘤细胞 (STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0411 | U-118 MG人脑星形胶质母细胞瘤 | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0412 | SK-N-BE(2)人神经母细胞瘤细胞 (STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0413 | SK-N-SH人神经母细胞瘤细胞 | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ505-K | 支原体检测试剂盒 | 1ml/100T | ¥800.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
1 | 慢病毒介导基因沉默或过表达 | ¥询价 | 放入购物车 》 | |
3 | 细菌基因敲除 | ¥询价 | 放入购物车 》 | |
ZQ-100 | DMEM(高糖)基础培养基 | 500ml | ¥56.00 | 放入购物车 》 |
ZQ-101 | DMEM(高糖)完全培养基 | 500ML | ¥350.00 | 放入购物车 》 |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |