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JEG-3人绒毛膜癌细胞(STR鉴定)

英文名:JEG-3
货号:ZQ0343
价格:¥1350.00
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推荐组合

JEG-3人绒毛膜癌细胞(STR鉴定)

¥1350.00
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JEG-3人绒毛膜癌细胞专用培养基

¥350.00 ¥480.00

配套完培,组合使用,省时省力

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细胞套餐惊爆价

¥1700 ¥1980.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

JEG-3人绒毛膜癌细胞

货号

ZQ0343

产品介绍

JEG-3细胞系来源于人类绒毛膜癌,绒毛膜癌是一种起源于胎盘滋养层细胞的癌症。细胞表现出滋养层细胞的特性,包括产生激素的能力,如人绒毛膜促性腺激素(hCG),这对维持妊娠至关重要。该细胞是一种超三倍体、克隆来源的人类细胞系,具有上皮形态,是从 Erwin-Turner 肿瘤的 Woods 株中分离出来的,其具有致瘤性,能够形成与绒毛膜癌一致的恶性肿瘤。表达的基因:人绒毛膜促性腺激素(hCG);人绒毛膜生长激素(胎盘催乳素);黄体酮。常用于胎盘功能、癌症生物学和内分泌信号的研究。
JEG-3细胞以其侵袭性生长特性和侵袭周围组织的能力而闻名,使其成为研究滋养层肿瘤侵袭和转移机制的重要模型。此外,它们已被广泛用于研究胎盘发育的分子途径,以及滋养细胞在怀孕期间免疫耐受中的作用。细胞通常在RPMI-1640培养基中培养,并添加胎牛血清和其他生长因子以支持其增殖和维持。
特别注意JEG-3细胞系严格用于研究目的,不应用于治疗应用或体内研究。该细胞系为研究胎盘癌生物学、激素产生以及滋养细胞与母体免疫系统之间的相互作用提供了一个强大的平台。

种属

性别/年龄

男/胎

组织

胎盘

疾病

绒膜癌

细胞类型

肿瘤细胞 

形态学

上皮的

生长方式

贴壁

倍增时间

大约24~36小时 

培养基和添加剂

MEM(品牌:中乔新舟 货号:ZQ-300+10%FBS(品牌:中乔新舟 货号:ZQ500-A+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0343

生物安全等级

BSL-1

STR位点信息

Amelogenin: X,Y

CSF1PO: 11,12

D13S317: 9,11

D16S539: 13,14

D5S818: 10,11

D7S820: 10,12

TH01: 9,9.3

TPOX: 8

vWA: 16

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

  ***

基因表达

  ***

保藏机构

ATCC; HTB-36 BCRC; 60428 BCRJ; 0123 DSMZ; ACC-463 ECACC; 92120308

供应限制

仅供科研使用

货号

ZQ0343

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: LncRNA TDRG1/miR‐214‐5p axis affects preeclampsia by modulating trophoblast cells
DOI: 10.1002/cbf.3480
发表时间: 2019-12-29
期刊: CELL BIOCHEMISTRY AND FUNCTION
影响因子: 2.142
货号: ZQ0343
产品名称: JEG-3 cells

原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbf.3480



PubMed=5103722; DOI=10.1210/jcem-32-5-683
Kohler P.O., Bridson W.E.
Isolation of hormone-producing clonal lines of human choriocarcinoma.
J. Clin. Endocrinol. Metab. 32:683-687(1971)


PubMed=62839; DOI=10.1093/jnci/56.5.911
Lieblich J.M., Weintraub B.D., Krauth G.H., Kohler P.O., Rabson A.S., Rosen S.W.
Ectopic and eutopic secretion of chorionic gonadotropin and its subunits in vitro: comparison of clonal strains from carcinomas of lung and placenta.
J. Natl. Cancer Inst. 56:911-917(1976)


PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)


PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)


PubMed=7459858
Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)


PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)


PubMed=2878840; DOI=10.1016/0020-7292(86)90088-3
Yamashita K., Nakamura T., Shimizu T., Katagiri M., Ikeda H.
Expression of HLA class I and class II antigens in human choriocarcinoma cell lines.
Int. J. Gynecol. Obstet. 24:301-307(1986)


PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)


PubMed=7937597; DOI=10.1016/0143-4004(94)90008-6
Grummer R., Hohn H.-P., Mareel M.M., Denker H.-W.
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15:411-429(1994)


PubMed=7753552
Brown A.D., Lopez-Terrada D.H., Denny C., Lee K.A.W.
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)


PubMed=7819056; DOI=10.1038/bjc.1995.3
Yaginuma Y., Yamashita T., Takuma N., Katayama H., Ishikawa M.
Analysis of the p53 gene in human choriocarcinoma cell lines.
Br. J. Cancer 71:9-12(1995)


DOI=10.1007/0-306-46861-1_8
Ganapathy V., Prasad P.D., Leibach F.H.
Choriocarcinoma.
(In) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.141-147; Kluwer Academic Publishers; New York (1999)


PubMed=11994546; DOI=10.1093/molehr/8.5.485
Blanchon L., Sauvant P., Bavik C., Gallot D., Charbonne F., Alexandre-Gouabau M.-C., Lemery D., Jacquetin B., Dastugue B., Ward S., Sapin V.
Human choriocarcinoma cell line JEG-3 produces and secretes active retinoids from retinol.
Mol. Hum. Reprod. 8:485-493(2002)


PubMed=12966428; DOI=10.1038/sj.bjc.6601212
Li K.K.C., Goodall J., Goding C.R., Liao S.-K., Wang C.-H., Lin Y.-C., Hiraga H., Nojima T., Nagashima K., Schaefer K.-L., Lee K.A.W.
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)


PubMed=16797695; DOI=10.1016/j.placenta.2006.05.001
Burleigh D.W., Kendziorski C.M., Choi Y.J., Grindle K.M., Grendell R.L., Magness R.R., Golos T.G.
Microarray analysis of BeWo and JEG3 trophoblast cell lines: identification of differentially expressed transcripts.
Placenta 28:383-389(2007)


PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)


PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)


PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)


PubMed=28161053; DOI=10.1016/j.placenta.2016.12.007
Abou-Kheir W., Barrak J., Hadadeh O., Daoud G.
HTR-8/SVneo cell line contains a mixed population of cells.
Placenta 50:1-7(2017)


PubMed=28724925; DOI=10.1038/s41598-017-06364-z
Rothbauer M., Patel N., Gondola H., Siwetz M., Huppertz B., Ertl P.
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892-5892(2017)


PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)


PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Weber M., Weise A., Vasheghani F., Gohner C., Fitzgerald J.S., Liehr T., Markert U.R.
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)


PubMed=33810901; DOI=10.1016/j.placenta.2021.02.022
Pastuschek J., Nonn O., Gutierrez-Samudio R.N., Murrieta-Coxca J.M., Muller J., Sanft J., Huppertz B., Markert U.R., Groten T., Morales-Prieto D.M.
Molecular characteristics of established trophoblast-derived cell lines.
Placenta 108:122-133(2021)


PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)


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