产品名称 |
NCI-H1975人肺腺癌细胞 |
货号 |
ZQ0395 |
产品介绍 |
这株NCI-H1975 [H-1975,H1975]细胞是1988年从患有非小细胞肺癌的不吸烟女性的肺中分离的呈现上皮形态学的细胞系。
注意事项: |
种属 |
人 |
性别/年龄 |
女 |
组织 |
肺 |
疾病 |
腺癌;非小细胞肺癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
上皮的 |
生长方式 |
贴壁 |
倍增时间 |
大约28~42.2小时 |
培养基和添加剂 |
PMI-1640基础培养基(品牌:中乔新舟 货号:ZQ-200)+10%FBS(品牌:中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006)+1%L-alanyl-L-glutamine(中乔新舟 货号:CSP004 )+1%Sodium Pyruvate 100 mM Solution(中乔新舟 货号:CSP003) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X; CSF1PO: 12; D13S317: 10,13; D16S539: 9,12; D5S818: 11,12; D7S820: 8,11; THO1: 7; TPOX: 8,11; vWA: 18 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; CRL-5908 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0395 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
原文链接: https://cancerci.biomedcentral.com/articles/10.1186/s12935-021-02341-9
论文标题: LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression
DOI: 10.1093/carcin/bgab047
发表时间: 2021-07-16
期刊: CARCINOGENESIS
影响因子: 4.944
货号: ZQ0395
产品名称: H1975 cell
原文链接: https://academic.oup.com/carcin/advance-article-abstract/doi/10.1093/carcin/bgab047/6295508
论文标题: Lobaplatin Enhances Radioactive 125I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway
DOI: 10.2147/OTT.S288012
发表时间: 2021-01-12
期刊: OncoTargets and Therapy
影响因子: 4.147
货号: ZQ0395
产品名称: H1975 cell
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811486/
论文标题: Correlations of the ZEB1 expression with the incidence and prognosis of non-small cell lung cancer.
DOI: 10.26355/eurrev_201902_17111
发表时间: 2019-02-01
期刊: European Review for Medical and Pharmacological Sciences
影响因子: 2.721
货号: ZQ0395
产品名称: NCI-H1975 cells
原文链接: https://europepmc.org/article/med/30840275?javascript_support=no
PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
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Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification.
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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
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Systems-level modeling of cancer-fibroblast interaction.
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Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)
PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)
PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x
Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)
PubMed=21498706
Onitsuka T., Uramoto H., Tanaka F.
Lack of direct association between EGFR mutations and ER beta expression in lung cancer.
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PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112
Byers L.A., Wang J., Nilsson M.B., Fujimoto J., Saintigny P., Yordy J., Giri U., Peyton M., Fan Y.-H., Diao L.-X., Masrorpour F., Shen L., Liu W.-B., Duchemann B., Tumula P., Bhardwaj V., Welsh J., Weber S., Glisson B.S., Kalhor N., Wistuba I.I., Girard L., Lippman S.M., Mills G.B., Coombes K.R., Weinstein J.N., Minna J.D., Heymach J.V.
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
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PubMed=25008024; DOI=10.1007/s10735-014-9583-2
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The reverse effect of X-ray irradiation on acquired gefitinib resistance in non-small cell lung cancer cell line NCI-H1975 in vitro.
J. Mol. Histol. 45:641-652(2014)
PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
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PubMed=25483995; DOI=10.3892/mmr.2014.3058
Zhao B.-X., Wang J., Song B., Wei H., Lv W.-P., Tian L.-M., Li M., Lv S.
Establishment and biological characteristics of acquired gefitinib resistance in cell line NCI-H1975/gefinitib-resistant with epidermal growth factor receptor T790M mutation.
Mol. Med. Rep. 11:2767-2774(2015)
货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ505-K | 支原体检测试剂盒 | 1ml/100T | ¥800.00 | 放入购物车 》 |
ZQ506 | 支原体清除试剂盒 | 1ml | ¥600.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
1 | 慢病毒介导基因沉默或过表达 | ¥询价 | 放入购物车 》 | |
5 | 荧光素酶标记 | ¥询价 | 放入购物车 》 | |
6 | 绿/红色荧光蛋白标记 | ¥询价 | 放入购物车 》 | |
ZQ-200 | RPMI-1640基础培养基 | 500ml | ¥56.00 | 放入购物车 》 |
ZQ-201 | RPMI-1640完全培养基 | 500ml | ¥350.00 | 放入购物车 》 |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |
0513 | 双抗(青霉素/链霉素)溶液 | 100ml | ¥384.00 | 放入购物车 》 |
0563 | 支原体抑制剂 10 mg/ml; 1 ml(定制) | 10 mg/ml; 10 x 1 ml | ¥1808.00 | 放入购物车 》 |
JSFW-134 | 人源细胞STR鉴定服务 | ¥900.00 | 放入购物车 》 |