产品名称 |
143B人骨肉瘤细胞 |
货号 |
ZQ0455 |
产品介绍 |
143B细胞是一种人类骨肉瘤细胞系,最初是从一位患有骨肉瘤的13岁白人女性的骨骼中分离出来的。骨肉瘤是一种恶性骨肿瘤,主要影响青少年,通常发生在生长迅速的骨骼区域,如膝关节附近。 该细胞是合适的转染宿主,可用于癌症研究。 |
种属 |
人 |
性别/年龄 |
女性/13岁 |
组织 |
骨 |
疾病 |
骨肉瘤 |
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X X
|
细胞类型 |
肿瘤细胞 |
形态学 |
上皮样混合形 |
生长方式 |
贴壁 |
倍增时间 |
大约36小时 |
培养基和添加剂 |
EMEM(货号:ZQ-300)+10%FBS(货号:ZQ-500-A)+1%PS(货号:CSP006) +0.015mg/ml 5-溴-2-脱氧尿苷 |
推荐完全培养基货号 |
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC = CRL-8303;BCRC = 60439;CCRIDECACC = 91112502 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0455 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: Fructose-coated Angstrom silver inhibits osteosarcoma growth and metastasis via promoting ROS-dependent apoptosis through the alteration of glucose metabolism by inhibiting PDK
DOI: 10.7150/thno.45858
发表时间: 2020-06-19
期刊: Theranostics
影响因子: 8.579
货号: ZQ0455
产品名称: 143B cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7359101/
论文标题: Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo
DOI: 10.3389/fphar.2019.00307
发表时间: 2019-03-28
期刊: Frontiers in Pharmacology
影响因子: 5.811
货号: ZQ0455
产品名称: 143B cell lines
原文链接: https://www.frontiersin.org/articles/10.3389/fphar.2019.00307/full
论文标题: ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p
DOI: 10.1186/s12935-020-01174-2
发表时间: 2020-03-30
期刊: Cancer Cell International
影响因子: 5.722
货号: ZQ0455
产品名称: 143B cells
原文链接: https://cancerci.biomedcentral.com/articles/10.1186/s12935-020-01174-2
论文标题: NPR3, transcriptionally regulated by POU2F1, inhibits osteosarcoma cell growth through blocking the PI3K/AKT pathway
DOI: 10.1016/j.cellsig.2021.110074
发表时间: 2021-07-03
期刊: CELLULAR SIGNALLING
影响因子: 4.315
货号: ZQ0455
产品名称: 143B cells
原文链接: https://www.sciencedirect.com/science/article/pii/S0898656821001637
论文标题: Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells
DOI: 10.2147/OTT.S232718
发表时间: 2020-02-21
期刊: OncoTargets and Therapy
影响因子: 4.147
货号: ZQ0455
产品名称: 143B cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041606/
论文标题: Circular RNA circVRK1 suppresses the proliferation, migration and invasion of osteosarcoma cells by regulating zinc finger protein ZNF652 expression via microRNA miR-337-3p
DOI: 10.1080/21655979.2021.1965695
发表时间: 2021-08-23
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0455
产品名称: 143B cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1965695
论文标题: Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress:
DOI: 10.1177/09603271221074346
发表时间: 2022-02-07
期刊: HUMAN & EXPERIMENTAL TOXICOLOGY
影响因子: 2.903
货号: ZQ0455
产品名称: 143B
原文链接: https://journals.sagepub.com/doi/abs/10.1177/09603271221074346
论文标题: MCAM is associated with metastasis and poor prognosis in osteosarcoma by modulating tumor cell migration
DOI: 10.1002/jcla.24214
发表时间: 2021-12-27
期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS
影响因子: 2.352
货号: ZQ0455
产品名称: human OS cell line 143B
原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1002/jcla.24214
论文标题: MicroRNA-506-3p initiates mesenchymal-to-epithelial transition and suppresses autophagy in osteosarcoma cells by directly targeting SPHK1
DOI: 10.1080/09168451.2019.1569496
发表时间: 2019-01-23
期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
影响因子: 1.297
货号: ZQ0455
产品名称: 143B cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/09168451.2019.1569496
PubMed=2233717; DOI=10.1128/mcb.10.11.5772-5781.1990
Diller L., Kassel J., Nelson C.E., Gryka M.A., Litwak G., Gebhardt M., Bressac B., Ozturk M., Baker S.J., Vogelstein B., Friend S.H.
p53 functions as a cell cycle control protein in osteosarcomas.
Mol. Cell. Biol. 10:5772-5781(1990)
PubMed=19787792; DOI=10.1002/gcc.20717
Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S.E., Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H., Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W., Buerger H., Aigner T., Gabbert H.E., Poremba C.
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)
PubMed=21519327; DOI=10.1038/labinvest.2011.72
Mohseny A.B., Machado I., Cai Y.-P., Schaefer K.-L., Serra M., Hogendoorn P.C.W., Llombart-Bosch A., Cleton-Jansen A.-M.
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)
PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
PubMed=23144859; DOI=10.1371/journal.pone.0048262
Kresse S.H., Rydbeck H., Skarn M., Namlos H.M., Barragan-Polania A.H., Cleton-Jansen A.-M., Serra M., Liestol K., Hogendoorn P.C.W., Hovig E., Myklebost O., Meza-Zepeda L.A.
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PLoS ONE 7:E48262-E48262(2012)
货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ505-K | 支原体检测试剂盒 | 1ml/100T | ¥800.00 | 放入购物车 》 |
ZQ506 | 支原体清除试剂盒 | 1ml | ¥600.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
1 | 慢病毒介导基因沉默或过表达 | ¥询价 | 放入购物车 》 | |
5 | 荧光素酶标记 | ¥询价 | 放入购物车 》 | |
6 | 绿/红色荧光蛋白标记 | ¥询价 | 放入购物车 》 | |
ZQ-300 | MEM(含有NEAA)基础培养基 | 500ml | ¥56.00 | 放入购物车 》 |
ZQ-301 | EMEM(含有NEAA)完全培养基 | 500ml | ¥350.00 | 放入购物车 》 |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |
0513 | 双抗(青霉素/链霉素)溶液 | 100ml | ¥384.00 | 放入购物车 》 |
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