产品名称 |
min6小鼠胰岛瘤细胞 |
货号 |
ZQ0462 |
产品介绍 |
min6细胞分泌胰岛素、胰高血糖素、生长抑素和胃饥饿素。 |
种属 |
小鼠 |
组织来源 |
胰腺 |
形态学 |
上皮细胞样 |
细胞类型 |
转化细胞系 |
换液频率 |
2-3次/周 |
生长方式 |
贴壁 |
培养基和添加剂 |
DMEM (中乔新舟 货号:ZQ-100)+10%FBS(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
保藏机构 |
AddexBio; C0018008/403 BCRJ; 0293 IBRC; C10524 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0462 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1996314
PubMed=2163307; DOI=10.1210/endo-127-1-126
Miyazaki J.-i., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K.-i.
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms.
Endocrinology 127:126-132(1990)
PubMed=8697299
Poitout V., Olson L.K., Robertson R.P.
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)
PubMed=8824267; DOI=10.1074/jbc.271.42.26194
Soejima A., Inoue K., Takai D., Kaneko M., Ishihara H., Oka Y., Hayashi J.-i.
Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.
J. Biol. Chem. 271:26194-26199(1996)
PubMed=18845907; DOI=10.1507/endocrj.K08E-172
Nakashima K., Kanda Y., Hirokawa Y., Kawasaki F., Matsuki M., Kaku K.
MIN6 is not a pure beta cell line but a mixed cell line with other pancreatic endocrine hormones.
Endocr. J. 56:45-53(2009)
PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)
PubMed=22808281; DOI=10.1371/journal.pone.0040868
Cheng K., Delghingaro-Augusto V., Nolan C.J., Turner N., Hallahan N., Andrikopoulos S., Gunton J.E.
High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.
PLoS ONE 7:E40868-E40868(2012)
PubMed=23560115; DOI=10.1371/journal.pone.0061211
Yamato E., Tashiro F., Miyazaki J.-i.
Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic beta cell line MIN6.
PLoS ONE 8:E61211-E61211(2013)
PubMed=25546123; DOI=10.1002/pmic.201400345
Lee J.-S., Wu Y.-N., Schnepp P., Fang J.-Y., Zhang X.-B., Karnovsky A., Woods J., Stemmer P.M., Liu M., Zhang K.-Z., Chen X.-Q.
Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.
Proteomics 15:1508-1511(2015)
PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)
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