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Mono-Mac-6人急性单核细胞白血病细胞 (STR鉴定)
英文名:Mono-Mac-6
货号:ZQ1028
价格:¥1800.00
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推荐组合

Mono-Mac-6人急性单核细胞白血病细胞 (STR鉴定)

¥1800.00
+

Mono-Mac-6人急性单核细胞白血病细胞专用培养基

¥550.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥2350
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

Mono-Mac-6人急性单核细胞白血病细胞

货号

ZQ1028

产品介绍

Mono-Mac-6细胞系源自一名64岁男性患者,该患者患有复发性急性单核细胞白血病(AML FAB M5)。细胞系建立于1985年,从患者的外周血单核细胞中获得。在培养中呈现为悬浮生长的单个、圆形/多形性细胞或小细胞群,有时松散粘附。Mono-Mac-6细胞系是研究急性单核细胞白血病(AMoL或AML-M5)的理想模型,尤其在探讨单核细胞在外周血中异常增生的病理机制方面。此外,该细胞系还可用于药物筛选、免疫学研究、细胞信号传导研究等领域。因其独特的特性和功能,在急性单核细胞白血病的研究中扮演着重要角色,为理解该疾病的发病机制和开发新的治疗方法提供了重要的实验工具。

备注:该细胞对胎牛血清品质比较敏感,需要用到优质胎牛血清进行培养,当细胞生长出现缓慢时,建议提高血清浓度到20%,或者更换更优质的胎牛血清来培养。

种属

性别/年龄

/64岁

组织

外周血

疾病

急性单核细胞白血病

细胞类型

肿瘤细胞

形态学

圆形

生长方式

悬浮

倍增时间

40 hours (PubMed=25984343); ~60 hours (DSMZ=ACC-124)

培养基和添加剂

RPMI-1640(品牌:中乔新舟 货号:ZQ-200+10%胎牛血清(中乔新舟 货号:ZQ0500+1%双抗(中乔新舟  货号:CSP006+10ug/mL Insulin(中乔新舟 货号:CSP001-10

推荐完全培养基货号

ZM1028

培养条件

95%空气,5%二氧化碳;37℃

STR位点信息

Amelogenin: X

CSF1PO 11,12

D2S1338 19,23

D3S1358 14,18

D5S818 11,12

D7S820 10,11

D8S1179 10,12

D13S317 11,12

D16S539 12

D18S51 13,14

D19S433 13,14

D21S11 30,31.2

FGA 20,22

Penta D 9,11

Penta E 10,11

TH01 8,9.3

TPOX 8,10

vWA 17

生物安全等级

BSL-1

保藏机构

BCRJ; 0373;DSMZ; ACC-124

供应限制

仅供科研使用


货号

ZQ1028

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用

PubMed=3162233; DOI=10.1002/ijc.2910410324
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PubMed=25984343; DOI=10.1038/sdata.2014.35
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PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
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