产品名称	HEK-293人胚肾细胞
货号	ZQ0034
产品介绍	尽管较早的报道说这株细胞包含腺病毒5 DNA病毒基因组的左端和右端，现在已经清楚只存在左端序列。这株细胞适于滴定人腺病毒。细胞表达一种不寻常的由整联蛋白beta-1亚基和玻联蛋白alpha-v亚基组成的玻联蛋白细胞表面受体。Ad5插入片段进行了克隆和测序，结果表明碱基1-4344插入到了19号染色体（19q13.2）。293细胞比较容易转染，是一个很常用的表达研究外源基因的细胞株。293细胞的缺陷是生长过程中贴壁强度比较小。所以在实验过程中容易流失，从而影响实验结果。
种属	人
性别/年龄	女
组织	胚肾
疾病	常态
生物安全等级	BSL 2
STR位点信息	Amelogenin: X CSF1PO: 11,12 D13S317: 12,14 D16S539: 9,13 D5S818: 8,9 D7S820: 11,12 TH01: 7,9.3 TPOX: 11 vWA: 16,19
细胞类型	转化细胞系
形态学	上皮细胞样
生长方式	贴壁（弱）
倍增时间	大约24~30小时
培养基和添加剂	MEM（含NEAA）（品牌：中乔新舟 货号：ZQ-300）+10%FBS（货号：ZQ500-A）+1%PS（货号：CSP006）
推荐完全培养基货号	ZM0034
培养条件	95%空气，5%二氧化碳；37℃
抗原表达/受体表达
基因表达
细胞来源	ATCC
供应限制	仅供科研使用

货号	ZQ0034
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

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23、论文标题： Photodegradation of carbon dots cause cytotoxicity DOI： 10.1038/s41467-021-21080-z 发表时间： 2021-02-05 期刊： Nature Communications 影响因子： 14.919 货号： ZQ0034 产品名称： HEK-293 cells 原文链接： https://www.nature.com/articles/s41467-021-21080-z 24、论文标题： Triple-serotype chimeric oncolytic adenovirus exerts multiple synergistic mechanisms against solid tumors DOI： 10.1136/jitc-2022-004691 发表时间： 2022-05-01 期刊： Journal for ImmunoTherapy of Cancer 影响因子： 13.751 货号： ZQ0034 产品名称： HEK293 cells 原文链接： https://jitc.bmj.com/content/10/5/e004691.abstract 25、论文标题： Depleting SOX2 improves ischemic stroke via lncRNA PVT1/microRNA-24-3p/STAT3 axis DOI： 10.1186/s10020-021-00346-8 发表时间： 2021-09-14 期刊： MOLECULAR MEDICINE 影响因子： 6.354 货号： ZQ0034 产品名称： HEK293 cells 原文链接： https://link.springer.com/article/10.1186/s10020-021-00346-8 26、论文标题： LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells DOI： 10.1016/j.fct.2021.112350 发表时间： 2021-06-15 期刊： FOOD AND CHEMICAL TOXICOLOGY 影响因子： 6.025 货号： ZQ0034 产品名称： HEK293 cells 原文链接： https://www.sciencedirect.com/science/article/pii/S0278691521003835 27、论文标题： Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells DOI： 10.1016/j.fct.2021.112055 发表时间： 2021-02-09 期刊： FOOD AND CHEMICAL TOXICOLOGY 影响因子： 6.025 货号： ZQ0034 产品名称： HEK293 cells 原文链接： https://www.sciencedirect.com/science/article/pii/S0278691521000892

28、论文标题： Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells
DOI： 10.1016/j.fct.2020.111740
发表时间： 2020-09-07
期刊： FOOD AND CHEMICAL TOXICOLOGY
影响因子： 4.679
货号： ZQ0034
产品名称： HEK293 cells
原文链接： https://www.sciencedirect.com/science/article/pii/S027869152030630X

29、论文标题： N-Acetylcysteine Inhibits Patulin-Induced Apoptosis by Affecting ROS-Mediated Oxidative Damage Pathway
DOI： 10.3390/toxins13090595
发表时间： 2021-08-26
期刊： Toxins
影响因子： 4.546
货号： ZQ0034
产品名称： HEK293 cells
原文链接： https://www.mdpi.com/2072-6651/13/9/595

30、论文标题： Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway
DOI： 10.1021/acs.jafc.8b01212
发表时间： 2018-04-20
期刊： JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子： 3.412
货号： ZQ0034
产品名称： HEK293 cell lines
原文链接： https://pubs.acs.org/doi/abs/10.1021/acs.jafc.8b01212

31、论文标题： Inhibition of microRNA-182-5p contributes to attenuation of lupus nephritis via Foxo1 signaling
DOI： 10.1016/j.yexcr.2018.09.026
发表时间： 2018-10-09
期刊： EXPERIMENTAL CELL RESEARCH
影响因子： 3.309
货号： ZQ0034
产品名称： HEK293 cells
原文链接： https://www.sciencedirect.com/science/article/pii/S0014482718310383

32、论文标题： CRMP5 regulates cell proliferation and development of colorectal cancer via MAPK‑dependent signaling
DOI： 10.3892/ol.2021.13008
发表时间： 2021-08-24
期刊： Oncology Letters
影响因子： 2.967
货号： ZQ0034
产品名称： 293 cells
原文链接： https://www.spandidos-publications.com/10.3892/ol.2021.13008

33、论文标题： Disabled-2 overexpression mediates immune suppression in systemic lupus erythematosus by modulating Treg/Th17 cell differentiation
DOI： 10.1111/1440-1681.13630
发表时间： 2022-02-16
期刊： CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
影响因子： 2.557
货号： ZQ0034
产品名称： HEK-293 cells
原文链接： https://onlinelibrary.wiley.com/doi/abs/10.1111/1440-1681.13630

34、论文标题： Recombinant PAL/PilE/FlaA DNA vaccine provides protective immunity against Legionella pneumophila in BALB/c mice
DOI： 10.1186/s12896-020-00620-3
发表时间： 2020-05-18
期刊： BMC BIOTECHNOLOGY
影响因子： 2.312
货号： ZQ0034
产品名称： 293 cells
原文链接： https://bmcbiotechnol.biomedcentral.com/articles/10.1186/s12896-020-00620-3