产品名称 |
4T1小鼠乳腺癌细胞 |
货号 |
ZQ0201 |
产品介绍 |
4T1是一种6-硫鸟嘌呤抗性细胞系,选自410.4肿瘤,未经诱变剂治疗。4T1细胞在BALB/C小鼠体内的肿瘤生长和转移扩散与人乳腺癌非常相似。这种肿瘤是人类乳腺癌第四阶段的动物模型。当注射到BALB/C小鼠体内时,4T1会自发产生高转移性肿瘤,在原发肿瘤原位生长的同时转移到肺、肝、淋巴结和大脑。4T1诱导的肿瘤既可以作为术后模型,也可以作为非手术模型,因为4T1诱导的肿瘤在两个具有相似动力学的模型中自发转移。 注意事项:该细胞培养中不要使其生长至完全融合,应该在达到90%融合度时传代。吸弃培养基,用0.25%胰蛋白酶(含0.53 mM EDTA)溶液冲洗。吸走溶液,再添加1到2毫升胰蛋白酶EDTA溶液。让培养瓶在室温(或37°C)下放置,直到大多数细胞从培养瓶底面脱落。加入新鲜培养基,吹打均匀并分配到新的培养瓶中。 |
种属 |
小鼠 |
组织来源 |
乳腺组织 |
形态学 |
上皮细胞样 |
细胞类型 |
肿瘤细胞系 |
倍增时间 |
12.6 hours (ATCC=CRL-2539). |
生长方式 |
贴壁 |
培养基和添加剂 |
RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%双抗(中乔新舟 货号:CSP006)+1%L-alanyl-L-glutamine(中乔新舟 货号:CSP004) +1%Non-essential Amino Acids, 100 (中乔新舟 货号:CSP008)+1% Sodium Pyruvate 100 mM Solution(中乔新舟 货号:CSP003) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
保藏机构 |
AddexBio; C0006004/13 ATCC; CRL-2539 BCRJ; 0022 CCTCC; GDC0294 CLS; 300300 |
供应限制 |
仅供科研使用 |
货号 |
ZM0201 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: A metabolic acidity-activatable calcium phosphate probe with fluorescence signal amplification capabilities for non-invasive imaging of tumor malignancy
DOI: 10.1016/j.scib.2021.11.003
发表时间: 2021-11-03
期刊: Science Bulletin
影响因子: 11.78
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://www.sciencedirect.com/science/article/pii/S2095927321006952
论文标题: Estimating dynamic vascular perfusion based on Er-based lanthanide nanoprobes with enhanced down-conversion emission beyond 1500 nm
DOI: 10.7150/thno.65771
发表时间: 2021-10-11
期刊: Theranostics
影响因子: 11.556
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581431/
论文标题: Mitochondria-targeted nanoplatforms for enhanced photodynamic therapy against hypoxia tumor
DOI: 10.1186/s12951-021-01196-6
发表时间: 2021-12-20
期刊: JOURNAL OF NANOBIOTECHNOLOGY
影响因子: 10.435
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01196-6
论文标题: A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases
DOI: 10.1186/s12951-021-01162-2
发表时间: 2021-12-19
期刊: JOURNAL OF NANOBIOTECHNOLOGY
影响因子: 10.435
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01162-2
论文标题: Cancer cell membrane-coated nanoparticles for bimodal imaging-guided photothermal therapy and docetaxel-enhanced immunotherapy against cancer
DOI: 10.1186/s12951-021-01202-x
发表时间: 2021-12-24
期刊: JOURNAL OF NANOBIOTECHNOLOGY
影响因子: 10.435
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01202-x
论文标题: Sulourea-coordinated Pd nanocubes for NIR-responsive photothermal/H2S therapy of cancer
DOI: 10.1186/s12951-021-01042-9
发表时间: 2021-10-14
期刊: JOURNAL OF NANOBIOTECHNOLOGY
影响因子: 10.435
货号: ZQ0201
产品名称: 4T1 breast cancer cells
原文链接: https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01042-9
论文标题: pH-Responsive Nanoparticles for Enhanced Antitumor Activity by High-Intensity Focused Ultrasound Therapy Combined with Sonodynamic Therapy
DOI: 10.2147/IJN.S336632
发表时间: 2022-01-25
期刊: International Journal of Nanomedicine
影响因子: 7.033
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8800590/
论文标题: Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation
DOI: 10.1016/j.ijbiomac.2019.09.189
发表时间: 2019-10-24
期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
影响因子: 6.953
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://www.sciencedirect.com/science/article/pii/S014181301936369X
论文标题: Multiple comparisons of three different sources of biomaterials in the application of tumor tissue engineering in vitro and in vivo
DOI: 10.1016/j.ijbiomac.2019.02.136
发表时间: 2019-02-23
期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
影响因子: 4.784
货号: ZQ0201
产品名称: 4T1 cells
原文链接: https://www.sciencedirect.com/science/article/pii/S0141813019308189
论文标题: Chinese herbal medicine Baoyuan Jiedu decoction inhibits the accumulation of myeloid derived suppressor cells in pre-metastatic niche of lung via TGF-β/CCL9 pathway
DOI: 10.1016/j.biopha.2020.110380
发表时间: 2020-06-15
期刊: BIOMEDICINE & PHARMACOTHERAPY
影响因子: 4.545
货号: ZQ0201
产品名称: 4T1 breast cancer cells
原文链接: https://www.sciencedirect.com/science/article/pii/S0753332220305734
论文标题: L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis
DOI: 10.1111/jam.15620
发表时间: 2022-05-11
期刊: JOURNAL OF APPLIED MICROBIOLOGY
影响因子: 3.772
货号: ZQ0201
产品名称: breast cancer cell line 4 T1
原文链接: https://sfamjournals.onlinelibrary.wiley.com/doi/abs/10.1111/jam.15620
论文标题: Rutin restrains the growth and metastasis of mouse breast cancer cells by regulating the microRNA-129-1-3p-mediated calcium signaling pathway
DOI: 10.1002/jbt.22794
发表时间: 2021-04-29
期刊: JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子: 3.652
货号: ZQ0201
产品名称: mouse 4T1 breast cancer cell line
原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1002/jbt.22794
论文标题: Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway
DOI: 10.2147/CMAR.S279800
发表时间: 2020-12-18
期刊: Cancer Management and Research
影响因子: 2.886
货号: ZQ0201
产品名称: 4T1 cell
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7755376/
PubMed=10411109; DOI=10.1023/A:1006689719505
Lelekakis M., Moseley J.M., Martin T.J., Hards D., Williams E., Ho P., Lowen D., Javni J., Miller F.R., Slavin J., Anderson R.L.
A novel orthotopic model of breast cancer metastasis to bone.
Clin. Exp. Metastasis 17:163-170(1999)
PubMed=26857856; DOI=10.1007/s13577-015-0127-1
Abe H., Wada H., Baghdadi M., Nakanishi S., Usui Y., Tsuchikawa T., Shichinohe T., Hirano S., Seino K.-i.
Identification of a highly immunogenic mouse breast cancer sub cell line, 4T1-S.
Hum. Cell 29:58-66(2016)
PubMed=27177471; DOI=10.1016/j.canlet.2016.05.005
Sasaki S.-i., Baba T., Nishimura T., Hayakawa Y., Hashimoto S.-i., Gotoh N., Mukaida N.
Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.
Cancer Lett. 378:23-32(2016)
PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)
货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ0071 | MCF-7人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0072 | MDA-MB-453人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0077 | ZR-75-1人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1600.00 | 放入购物车 》 |
ZQ0104 | SHZ-88大鼠乳腺癌细胞(种属鉴定) | 5 x 10^5 cells/vial | ¥1000.00 | 放入购物车 》 |
ZQ0116 | 人乳腺癌细胞BcaP-37(hela污染,暂不供应) | 5 x 10^5 cells/vial | ¥1200.00 | 放入购物车 》 |
ZQ0118 | MDA-MB-231人乳腺癌细胞(STR鉴定)[套餐促销] | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0346 | ZR-75-30人乳腺癌细胞 | 5 x 10^5 cells/vial | ¥1800.00 | 放入购物车 》 |
ZQ0367 | HCC1937人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0372 | Hs 578T人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0373 | MDA-MB-468人乳腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ505-K | 支原体检测试剂盒 | 1ml/100T | ¥800.00 | 放入购物车 》 |
ZQ506 | 支原体清除试剂盒 | 1ml | ¥600.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
ZQ-200 | RPMI-1640基础培养基 | 500ml | ¥56.00 | 放入购物车 》 |
ZQ-201 | RPMI-1640完全培养基 | 500ml | ¥350.00 | 放入购物车 》 |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |