产品名称 |
MM.1S人IgA-骨髓瘤细胞 |
货号 |
ZQ0485 |
产品介绍 |
MM.1S是一种人IgA-骨髓瘤细胞系,最初是从患有免疫球蛋白Aλ骨髓瘤的42岁黑人女性患者的外周血中分离的B淋巴母细胞建立的,这些细胞具有淋巴母细胞样的形态,并且既可以悬浮生长也可以轻微贴壁。可用于研究多发性骨髓瘤的疾病进展、药物治疗反应以及耐药性机制。对地塞米松敏感。
注意事项: |
种属 |
人 |
性别/年龄 |
女/42岁 |
组织 |
外周血 |
疾病 |
免疫球蛋白Aλ骨髓瘤 |
细胞类型 |
B淋巴细胞 |
形态学 |
淋巴母细胞 |
生长方式 |
半悬浮 |
倍增时间 |
大约72~80小时 |
培养基和添加剂 |
RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%双抗(中乔新舟 货号:CSP006)+1% Sodium Pyruvate 100 mM Solution(中乔新舟 货号:CSP003) +1%L-alanyl-L-glutamine(中乔新舟 货号:CSP004) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
文献报道抗原表达CD25、CD38、CD52和CD59,糖皮质激素受体。 |
基因表达 |
*** |
保藏机构 |
ATCC; CRL-2974 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0485 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
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Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
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A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)
货号 | 产品名称 | 规格 | 价格 | 指令 |