产品名称 |
PC-3人前列腺癌细胞 |
货号 |
ZQ0040 |
产品介绍 |
人前列腺癌细胞PC-3来源于一名62岁IV级前列腺癌白人男性患者的骨髓转移灶。此细胞酸性磷酸酶(acid phosphatase)和5-α-睾丸激素还原酶(testosterone-5-alpha reductase) 活性表达低。 |
种属 |
人 |
性别/年龄 |
男/62岁 |
组织 |
前列腺;来源于转移部位:骨 |
疾病 |
四级,腺癌 |
生物安全等级 |
1 |
STR位点信息 |
Amelogenin: X CSF1PO: 11 D13S317: 11 D16S539: 11 D5S818: 13 D7S820: 8,11 TH01: 6,7 TPOX: 8,9 vWA: 17 |
细胞类型 |
上皮 |
形态学 |
上皮 |
生长方式 |
贴壁,(该细胞在软琼脂中成蔟生长,并可适应悬浮培养) |
倍增时间 |
|
培养基和添加剂 |
F-12基础培养基(中乔新舟 货号: ZQ-400)+10%胎牛血清 (中乔新舟 货号:ZQ500-A)+1%P/S(货号:CSP006) |
推荐完全培养基货号 |
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
|
基因表达 |
|
保藏机构 |
ATCC; CRL-1435 ATCC; CRL-7934 DSMZ; ACC-465 ECACC; 90112714 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0040 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
Kaighn ME, et al. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest. Urol. 17: 16-23, 1979. PubMed: 447482
Chen TR. Chromosome identity of human prostate cancer cell lines, PC-3 and PPC-1. Cytogenet. Cell Genet. 62: 183-184, 1993. PubMed: 8428522
Ohnuki Y, et al. Chromosomal analysis of human prostatic adenocarcinoma cell lines. Cancer Res. 40: 524-534, 1980. PubMed: 7471073
Sheng S, et al. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl. Acad. Sci. USA 93: 11669-11674, 1996. PubMed: 8876194
Umekita Y, et al. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride. Proc. Natl. Acad. Sci. USA 93: 11802-11807, 1996. PubMed: 8876218
Carter RE, et al. Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase. Proc. Natl. Acad. Sci. USA 93: 749-753, 1996. PubMed: 8570628
Nupponen NN, et al. Genetic alterations in prostate cancer cell lines detected by comparative genomic hybridization. Cancer Genet. Cytogenet. 101: 53-57, 1998. PubMed: 9460501
Geiger T, et al. Antitumor activity of a PKC-alpha antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted into nude mice. Anticancer Drug Des. 13: 35-45, 1998. PubMed: 9474241
Su ZZ, et al. Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. Proc. Natl. Acad. Sci. USA 93: 7252-7257, 1996. PubMed: 8692978
The cells form clusters in soft agar and can be adapted to suspension growth
The cells form clusters in soft agar and can be adapted to suspension growth
论文标题: Ångstrom‐Scale Silver Particles as a Promising Agent for Low‐Toxicity Broad‐Spectrum Potent Anticancer Therapy
DOI: 10.1002/adfm.201808556
发表时间: 2019-02-27
期刊: ADVANCED FUNCTIONAL MATERIALS
影响因子: 15.621
货号: ZQ0040
产品名称: PC-3 cells
原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201808556
论文标题: A metabolic acidity-activatable calcium phosphate probe with fluorescence signal amplification capabilities for non-invasive imaging of tumor malignancy
DOI: 10.1016/j.scib.2021.11.003
发表时间: 2021-11-03
期刊: Science Bulletin
影响因子: 11.78
货号: ZQ0040
产品名称: PC-3 cells
原文链接: https://www.sciencedirect.com/science/article/pii/S2095927321006952
论文标题: FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation
DOI: 10.1007/s00018-022-04320-3
发表时间: 2022-05-02
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES
影响因子: 9.261
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://link.springer.com/article/10.1007/s00018-022-04320-3
论文标题: Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages
DOI: 10.2147/IJN.S304515
发表时间: 2021-04-20
期刊: International Journal of Nanomedicine
影响因子: 6.4
货号: ZQ0040
产品名称: PC-3 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8068512/
论文标题: BLM interaction with EZH2 regulates MDM2 expression and is a poor prognostic biomarker for prostate cancer
DOI: PMID:33948362
发表时间: 2021-04-15
期刊: American Journal of Cancer Research
影响因子: 6.166
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085859/
论文标题: HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation
DOI: 10.3892/ijo.2022.5327
发表时间: 2022-02-22
期刊: INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子: 5.65
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://www.spandidos-publications.com/10.3892/ijo.2022.5327
论文标题: PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1
DOI: 10.1186/s13046-019-1323-8
发表时间: 2019-08-05
期刊: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
影响因子: 5.646
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1323-8
论文标题: PLCε knockdown prevents serine/glycine metabolism and proliferation of prostate cancer by suppressing YAP
DOI: PMID:32064161
发表时间: 2020-01-01
期刊: American Journal of Cancer Research
影响因子: 5.177
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7017741/
论文标题: EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality
DOI: 10.3389/fonc.2020.01688
发表时间: 2020-11-02
期刊: Frontiers in Oncology
影响因子: 4.848
货号: ZQ0040
产品名称: PC3 cell lines
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667376/
论文标题: Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9
DOI: 10.3892/or.2021.8197
发表时间: 2021-09-28
期刊: ONCOLOGY REPORTS
影响因子: 3.906
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://www.spandidos-publications.com/10.3892/or.2021.8197
论文标题: The Long Non-Coding RNA IDH1-AS1 Promotes Prostate Cancer Progression by Enhancing IDH1 Enzyme Activity
DOI: 10.2147/OTT.S251915
发表时间: 2020-08-07
期刊: OncoTargets and Therapy
影响因子: 3.337
货号: ZQ0040
产品名称: PC3 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432214/
货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ0036 | 22RV1人前列腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1400.00 | 放入购物车 》 |
ZQ0037 | DU 145人前列腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1400.00 | 放入购物车 》 |
ZQ0039 | LNcapcloneFGC人前列腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1800.00 | 放入购物车 》 |
ZQ0041 | PC-3M人前列腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1500.00 | 放入购物车 》 |
ZQ0197 | RM-1小鼠前列腺癌细胞(种属鉴定) | 5 x 10^5 cells/vial | ¥1200.00 | 放入购物车 》 |
ZQ0353 | VCaP人前列腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥2000.00 | 放入购物车 》 |
ZQ505-K | 支原体检测试剂盒 | 1ml/100T | ¥800.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
1 | 慢病毒介导基因沉默或过表达 | ¥询价 | 放入购物车 》 | |
3 | 细菌基因敲除 | ¥询价 | 放入购物车 》 | |
7 | 细胞基因敲除 | ¥询价 | 放入购物车 》 | |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |
ZQ-400 | F-12基础培养基 | 500ml | ¥96.00 | 放入购物车 》 |
ZQ-401 | F-12完全培养基 | 500ml | ¥350.00 | 放入购物车 》 |