产品名称	MDA-MB-453人乳腺癌细胞
货号	ZQ0072
产品介绍	MDA-MB-453是一种人乳腺癌细胞系，1976年R. Cailleau等从一位48岁女性肿瘤转移患者胸水中建立了该细胞株，其它转移灶包括淋巴结,脑和胸水及心包腔积水。该细胞过表达FGF受体。MDA-MB-453细胞提供了一个有价值的工具，用于研究乳腺癌的生物学特性、激素受体的作用、以及开发新的治疗策略。 注意事项： （1）MDA-MB-453细胞形态是贴壁细胞，贴壁细胞形态是上皮样（立方形或多边形）和圆形细胞。 （2）细胞刚复苏时细胞形态为圆形贴壁细胞，需要生长5天左右才会有上皮样贴壁细胞出现。 （3）细胞培养若使用的L-15基础培养液必须在没有CO2平衡的环境中培养细胞。
种属	人
性别/年龄	女/51岁
组织	乳腺/乳房；来源于转移部位:胸腔积液
疾病	腺癌
细胞类型	肿瘤细胞
形态学	上皮细胞
生长方式	半悬浮
倍增时间	大约38~68.8小时
培养基和添加剂（默认）	RPMI-1640（品牌：中乔新舟 货号：ZQ-200）+10%FBS（中乔新舟 货号：ZQ0500）+1%双抗（中乔新舟   货号：CSP006） 注意默认方案培养条件：95%空气，5%CO2；37℃
培养方案B（可选）	L-15（中乔新舟  货号：ZQ-1100）+10%胎牛血清（中乔新舟  货号：ZQ500-A）+1%双抗（中乔新舟   货号：CSP006） 注意B方案培养条件：100%空气；37℃
推荐默认完全培养基货号	ZM0072
B方案完全培养基货号	ZM0072-B
生物安全等级	BSL-1
STR位点信息	Amelogenin: X CSF1PO: 10,12 D13S317: 12 D16S539: 9 D5S818: 11 D7S820: 10 TH01: 6 TPOX: 10 vWA: 17,18 D3S1358: 15 D21S11: 29,31 D18S51: 15,20 Penta_E: 11 Penta_D: 9,10 D8S1179: 10,12 FGA: 18,23 D19S433: 13,14 D2S1338: 23,24
默认方案培养条件	95%空气，5%CO2；37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC; CRL-12532 ATCC; HTB-26 ATCC; CRM-HTB-26 BCRC; 60425 BCRJ; 0164 DSMZ; ACC-732 ECACC; 92020424
供应限制	仅供科研使用

货号	ZQ0072
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

1、论文标题： Triple-serotype chimeric oncolytic adenovirus exerts multiple synergistic mechanisms against solid tumors
DOI： 10.1136/jitc-2022-004691
发表时间： 2022-05-01
期刊： Journal for ImmunoTherapy of Cancer
影响因子： 13.751
货号： ZQ0072
产品名称： MBA-MB-453 cells

原文链接： https://jitc.bmj.com/content/10/5/e004691.abstract

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