产品名称	SK-MES-1人肺鳞癌细胞
货号	ZQ0119
产品介绍	SK-MES-1是一种人肺鳞癌细胞系，最初由G. Trempe和L. J. Old（1970年）从一位65岁患有鳞状细胞癌的白人男性转移性胸腔积液中分离得到，上皮形态。 这种细胞系在癌症研究领域中非常重要，尤其是在研究肺鳞状细胞癌的生物学特性和潜在治疗策略方面。应用案例有：药物筛选和疗效评估、转移和侵袭机制研究、肿瘤微环境和免疫反应研究、药物耐受性研究、基因和蛋白质表达研究、上皮间充质转化（EMT）研究、长链非编码RNA研究、免疫原性细胞死亡研究等。这些应用展示了SK-MES-1细胞系在肺鳞癌研究中的多样性和重要性。 注意事项： SK-MES-1细胞贴壁性差，温度低时细胞容易收缩脱落漂浮。
种属	人
性别/年龄	男/65岁
组织	肺组织；来源于转移部位：胸腔积液
疾病	肺部鳞癌
生物安全等级	BSL-1
STR位点信息	Amelogenin: X,Y CSF1PO: 12 D13S317: 11 D16S539: 13 D5S818: 11 D7S820: 8 TH01: 6,9.3 TPOX: 8 vWA: 14 D3S1358: 16 D21S11: 29,30 Penta_E: 5,11 Penta_D: 12,13 D8S1179: 13,14 FGA: 20,24 D19S433: 14 D2S1338: 18,19 D18S51: 17
细胞类型	肿瘤细胞
形态学	上皮细胞
生长方式	贴壁生长
倍增时间	大约50小时
培养基和添加剂	90%DMEM高糖（中乔新舟  货号：ZQ-100）+10%FBS（中乔新舟 货号：ZQ0500）+1%PS（中乔新舟  货号：CSP006)
推荐完全培养基货号	ZM0119
培养条件	37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC、ECACC、DSMZ、
供应限制	仅供科研使用

1、论文标题： Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma
DOI： 10.1016/j.omto.2020.01.010
发表时间： 2020-02-08
期刊： Molecular Therapy-Oncolytics
影响因子： 7.2
货号： ZQ0119
产品名称： SK-MES-1 cells

原文链接： https://www.sciencedirect.com/science/article/pii/S2372770520300206

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