产品名称 |
C643人甲状腺癌细胞 |
货号 |
ZQ0321 |
产品介绍 |
C643细胞系由Mark等人于1987年从一名76岁男性间变性甲状腺癌的细针活检中建立。患者在确诊后5个月内死亡。甲状腺球蛋白mRNA的表达确定了该细胞系的甲状腺上皮起源。 |
种属 |
人 |
性别/年龄 |
男/76 |
组织 |
甲状腺 |
疾病 |
甲状腺未分化癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
上皮 |
生长方式 |
贴壁 |
倍增时间 |
大约23小时 |
培养基和添加剂 |
RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
D5S818: 11,12 D13S317: 8,10 D7S820: 9,12 D16S539: 9,13 vWA: 15,17 THO1: 9.3,10 Amelogenin: X,Y TPOX: 11,12 CSF1PO: 10,11 |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
供应限制 |
仅供科研使用 |
货号 |
ZQ0321 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: Co-Delivery of 131I and Prima-1 by Self-Assembled CD44-Targeted Nanoparticles for Anaplastic Thyroid Carcinoma Theranostics
DOI: 10.1002/adhm.202001029
发表时间: 2020-12-16
期刊: Advanced Healthcare Materials
影响因子: 7.367
货号: ZQ0321
产品名称: C643 ATC cells
原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202001029
论文标题: LncRNA PVT1 Acts as a Tumor Promoter in Thyroid Cancer and Promotes Tumor Progression by Mediating miR-423-5p-PAK3
DOI: 10.2147/CMAR.S283443
发表时间: 2020-12-30
期刊: Cancer Management and Research
影响因子: 2.886
货号: ZQ0321
产品名称: C643 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779291/
PubMed=2848260; DOI=10.1073/pnas.85.23.9302
Heldin N.-E., Gustavsson B., Claesson-Welsh L., Hammacher A., Mark J., Heldin C.-H., Westermark B.
Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line.
Proc. Natl. Acad. Sci. U.S.A. 85:9302-9306(1988)
PubMed=14522906
Frasca F., Vella V., Aloisi A., Mandarino A., Mazzon E., Vigneri R., Vigneri P.
p73 tumor-suppressor activity is impaired in human thyroid cancer.
Cancer Res. 63:5829-5837(2003)
PubMed=17465858; DOI=10.1089/thy.2006.0246
Lee J.-J., Foukakis T., Hashemi J., Grimelius L., Heldin N.-E., Wallin G., Rudduck C., Lui W.-O., Hoog A., Larsson C.
Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models.
Thyroid 17:289-301(2007)
PubMed=17725429; DOI=10.1089/thy.2007.0097
Meireles A.M., Preto A., Rocha A.S., Rebocho A.P., Maximo V., Pereira-Castro I., Moreira S., Feijao T., Botelho T., Marques R., Trovisco V., Cirnes L., Alves C., Velho S., Soares P., Sobrinho-Simoes M.
Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines.
Thyroid 17:707-715(2007)
PubMed=18713817; DOI=10.1210/jc.2008-1102
Schweppe R.E., Klopper J.P., Korch C.T., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A. III, Smallridge R.C., Haugen B.R.
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)
PubMed=19087340; DOI=10.1186/1471-2407-8-371
Ribeiro F.R., Meireles A.M., Rocha A.S., Teixeira M.R.
Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples.
BMC Cancer 8:371.1-371.11(2008)
PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)
PubMed=23833040; DOI=10.1210/jc.2013-2383
Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A.
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)
PubMed=25365311; DOI=10.1210/jc.2014-2359
Garg M., Okamoto R., Nagata Y., Kanojia D., Venkatesan S., Anand M.T., Braunstein G.D., Said J.W., Doan N.B., Ho Q., Akagi T., Gery S., Liu L.-Z., Tan K.T., Chang W.J., Yang H., Ogawa S., Koeffler H.P.
Establishment and characterization of novel human primary and metastatic anaplastic thyroid cancer cell lines and their genomic evolution over a year as a primagraft.
J. Clin. Endocrinol. Metab. 100:725-735(2015)
PubMed=26680454; DOI=10.1186/s12885-015-1955-9
Kasaian K., Wiseman S.M., Walker B.A., Schein J.E., Zhao Y.-J., Hirst M., Moore R.A., Mungall A.J., Marra M.A., Jones S.J.M.
The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy.
BMC Cancer 15:984.1-984.11(2015)
PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953
Landa I., Pozdeyev N., Korch C.T., Marlow L.A., Smallridge R.C., Copland J.A. III, Henderson Y.C., Lai S.Y., Clayman G.L., Onoda N., Tan A.-C., Garcia-Rendueles M.E.R., Knauf J.A., Haugen B.R., Fagin J.A., Schweppe R.E.
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)
PubMed=31368081; DOI=10.1007/s12020-019-02009-5
Pinto A.T., Pojo M., Simoes-Pereira J., Roque R., Saramago A., Roque L., Martins C., Andre S., Cabecadas J., Leite V., Cavaco B.M.
Establishment and characterization of a new patient-derived anaplastic thyroid cancer cell line (C3948), obtained through fine-needle aspiration cytology.
Endocrine 66:288-300(2019)
货号 | 产品名称 | 规格 | 价格 | 指令 |
ZQ0281 | TTA1人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1500.00 | 放入购物车 》 |
ZQ0304 | B-CPAP人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1800.00 | 放入购物车 》 |
ZQ0305 | 8305C人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0310 | ACT-1人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1500.00 | 放入购物车 》 |
ZQ0312 | BHT101人甲状腺癌细胞(STR鉴定) | 1 x 10^6 cells/vial | ¥1800.00 | 放入购物车 》 |
ZQ0314 | HTh-7人甲状腺癌细胞(STR鉴定)[套餐促销] | 5 x 10^5 cells/vial | ¥1200.00 | 放入购物车 》 |
ZQ0315 | Hth83人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1600.00 | 放入购物车 》 |
ZQ0316 | KHM-5M人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0317 | KMH-2人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1500.00 | 放入购物车 》 |
ZQ0318 | KTC-1人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1350.00 | 放入购物车 》 |
ZQ0319 | Ocut-2C人甲状腺癌细胞(STR鉴定) | 5 x 10^5 cells/vial | ¥1600.00 | 放入购物车 》 |
A1001-1 | 国产转染试剂 | 1ml | ¥800.00 | 放入购物车 》 |
1 | 慢病毒介导基因沉默或过表达 | ¥询价 | 放入购物车 》 | |
3 | 细菌基因敲除 | ¥询价 | 放入购物车 》 | |
ZQ-200 | RPMI-1640基础培养基 | 500ml | ¥56.00 | 放入购物车 》 |
ZQ-201 | RPMI-1640完全培养基 | 500ml | ¥350.00 | 放入购物车 》 |
ZQ500-A | 优级胎牛血清 | 500ml | ¥2580(开学促销) | 放入购物车 》 |