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HCT-8 [HRT-18]人回盲肠癌细胞(STR鉴定)

英文名:HCT-8 [HRT-18]
货号:ZQ0331
价格:¥1400.00
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HCT-8 [HRT-18]人回盲肠癌细胞(STR鉴定)

¥1400.00
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HCT-8 [HRT-18]人回盲肠癌细胞专用培养基

¥350.00 ¥450.00

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细胞套餐惊爆价

¥1750 ¥1850.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

HCT-8 [HRT-18]人回盲肠癌细胞

货号

ZQ0331

产品介绍

HCT-8细胞(HCT-8与HRT-18一样),也被称为人回盲部结直肠腺癌细胞,是一种上皮细胞系,角蛋白免疫过氧化物酶染色阳性,最初来源于一位67岁的白人男性回盲部腺癌患者。HCT-8细胞系建立于20世纪60年代末,广泛应用于癌症研究,特别是在研究结直肠癌的发病、转移和治疗反应方面。
形态学上,HCT-8细胞呈上皮样,呈多边形的单层生长模式。它们具有在贴壁和半悬浮培养中生长的能力,这是癌细胞转移的一些过渡阶段的特征。这一特性使它们在研究癌细胞侵袭和迁移方面特别有用。
基因典型上,HCT-8细胞是高三倍体,含有几种在结直肠癌中常见的染色体畸变,包括与癌症进展和耐药机制相关的突变和缺失。这种基因图谱支持它们在肿瘤学研究中的应用,特别是那些关注与肿瘤发生和耐药性有关的遗传途径的研究。
利用HCT-8细胞的研究对了解结直肠癌生物学做出了重大贡献,包括阐明了参与癌细胞增殖、凋亡和化疗耐药的分子途径。该细胞系仍然是研究新治疗药物疗效和探索结直肠癌分子机制的关键模型。

种属

性别/年龄

男/67岁

组织

结肠

疾病

回盲部结肠直肠腺癌

细胞类型

 肿瘤细胞

形态学

上皮的

生长方式

贴壁

倍增时间

大约27.49小时

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0331

生物安全等级

BSL-1

STR位点信息

Amelogenin: X,Y

CSF1PO: 12

D13S317: 8,11

D16S539: 12,13

D5S818: 13

D7S820: 10,12,11.3

TH01: 7,9.3

TPOX: 8,11

vWA: 18,19

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ECACC; 90032006;ATCC CCL-244

供应限制

仅供科研使用

货号

ZQ0331

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: microRNA-96 promotes occurrence and progression of colorectal cancer via regulation of the AMPKα2-FTO-m6A/MYC axis
DOI: 10.1186/s13046-020-01731-7
发表时间: 2020-11-12
期刊: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
影响因子: 7.068
货号: ZQ0331
产品名称: HCT-8 cells
原文链接: https://link.springer.com/article/10.1186/s13046-020-01731-7


论文标题: Kinase GSK3β functions as a suppressor in colorectal carcinoma through the FTO-mediated MZF1/c-Myc axis
DOI: 10.1111/jcmm.16291
发表时间: 2021-02-02
期刊: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子: 5.31
货号: ZQ0331
产品名称: HCT-8 cells

原文链接: https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.16291



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