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HEC-1-B人子宫内膜腺癌细胞(STR鉴定)

英文名:HEC-1-B
货号:ZQ0364
价格:¥1400.00
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HEC-1-B人子宫内膜腺癌细胞(STR鉴定)

¥1400.00
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HEC-1-B人子宫内膜腺癌细胞专用培养基

¥350.00 ¥480.00

配套完培,组合使用,省时省力

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细胞套餐惊爆价

¥1750 ¥1880.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

HEC-1-B人子宫内膜腺癌细胞

货号

ZQ0364

产品介绍

HEC-1-B细胞系是一种人子宫内膜腺癌细胞系,这是 HEC-1-A 的一个亚株。与 HEC-1-A 不同,该亚株在培养的第 135 天和第 190 天之间表现出稳定的生长期,恢复后看起来比亲本系更平坦且具有更多的路面图案。染色体的主要互补体是亲本观察到的两倍线。该细胞已广泛应用于与子宫内膜癌、激素反应和癌症药理学研究相关的生物医学研究中。已知该细胞表达雌激素和孕激素受体,使其成为研究子宫内膜癌进展和治疗中激素相关动力学的有价值的模型。这些细胞已被用于研究癌细胞增殖、分化以及对激素和化疗治疗的反应的分子机制。
在形态学上,HEC-1-B细胞呈典型的上皮样形态,呈单层生长。其特点是体外增殖能力强。遗传研究揭示了一些染色体的改变,这些改变被认为是导致这些细胞癌变表型的原因。使用HEC-1-B细胞系的研究有助于更深入地了解子宫内膜癌的发生,并为测试潜在的治疗药物提供了一个强大的系统。该细胞系也通常用于专注于癌细胞入侵和转移的研究,为支持这些过程的细胞行为提供了见解。

种属

性别/年龄

女/71岁

组织

子宫;子宫内膜

疾病

腺癌

细胞类型

肿瘤细胞 

形态学

上皮

生长方式

贴壁

倍增时间

大约72~96小时 

培养基和添加剂

MEM(含NEAA)(中乔新舟  货号:ZQ-300+10%胎牛血清(中乔新舟  货号:ZQ500-A)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0364

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 10,12

D13S317: 11,16

D16S539: 11,12

D5S818: 11,13

D7S820: 9,11

TH01: 6,7

TPOX: 8,11

vWA: 18

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ATCC; HTB-113 JCRB; JCRB1193 JCRB; NIHS0480

供应限制

仅供科研使用

货号

ZQ0364

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题:  Dachsous cadherin related 1 (DCHS1) is a novel biomarker for immune infiltration and epithelial-mesenchymal transition in endometrial cancer via pan-cancer analysis
DOI:10.1186/s13048-024-01478-1.
发表时间: 2024-8-9
期刊: Journal of Ovarian Research
影响因子: 3.8
货号: ZQ0364
产品名称:HEC-1B cells
原文链接:https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-024-01478-1


论文标题: Synaptotagmin-like protein 1 is a potential diagnostic and prognostic biomarker in endometrial cancer based on bioinformatics and experiments
DOI:10.1186/s13048-023-01097-2.
发表时间: 2023-1-19
期刊: Journal of Ovarian Research
影响因子: 3.8
货号: ZQ0364
产品名称:  HEC-1B cells
原文链接:https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-023-01097-2


论文标题: UBE2C is upregulated by estrogen and promotes epithelial-mesenchymal transition via p53 in endometrial cancer
DOI: 10.1158/1541-7786.MCR-19-0561
发表时间: 2019-01-01
期刊: MOLECULAR CANCER RESEARCH
影响因子: 4.484
货号: ZQ0364
产品名称: HEC-1B cells
原文链接: https://mcr.aacrjournals.org/content/18/2/204.abstract
 

论文标题: Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification
DOI: 10.2147/DDDT.S361955
发表时间: 2022-06-16
期刊: Drug Design Development and Therapy
影响因子: 4.319
货号: ZQ0364
产品名称: HEC-1-B cell lines
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208491/



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