欢迎您访问中乔新舟官网!400-038-9959我的购物车(0)
您当前的位置:首页 > 产品中心
小鼠IFN-γELISA试剂盒
英文名:Mouse IFN-γ ELISA Kit
货号:EK0375
价格:¥7020.00
加入购物车,提交订单信息之后,我们会第一时间与您取得联系!
  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

小鼠IFN-γELISA试剂盒描述:


       Interferon-γ (IFN-γ) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-γ, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-γ is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and it is vital for the control of microbial pathogens. IFN-γ is believed to be crucial for host defense against many infections. Genetically determined variability in IFN-γ and its expression might be important for the development of tuberculosis. IFN-γ activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-γ has important immunoregulatory functions. IFN-γ plays an important role in the control of neointima proliferation.5 The standard product used in this kit is recombinant mouse IFNγ, consisting of 134 amino acids with the molecular mass of 15.6 KDa. ScienCell's mouse IFN-γ ELISA Kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Mouse IFN-γ-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The mouse specific detection polyclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added, and unbound conjugates re washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes into yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of mouse IFN-γ captured in strips.


产品使用说明:仅供科研研究使用

货号

EK0375

产地

美国

缩写

mIFN-γ-ELISA

规格

96 tests

用途

科研

保存

频繁使用存储在4°C,很少使用存储在-20°C

运输

胶冰

参考文献

1. Awad, M.; Pravica, V.; Perrey, C.; El Gamel, A.; Yonan, N.; Sinnott, P. J.; Hutchinson, I. V. CA repeat allele polymorphism in the first intron of the human interferon-γ gene is associated with lung allograft fibrosis. Hum.Immunol. 60: 343-346, 1999.
2. Szabo, S. J.; Sullivan, B. M.; Stemmann, C.; Satoskar, A. R.; Sleckman, B. P.; Glimcher, L. H. Distinct effects of T-bet in T(H)1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science 295: 338-342, 2002.
3. Rossouw, M.; Nel, H. J.; Cooke, G. S.; van Helden, P. D.; Hoal, E. G. Association between tuberculosis and a polymorphic NF-kappa-B binding site in the interferon gamma gene. Lancet 361: 1871-1872, 2003.
4. Nathan, C. F.; Murray, H. W.; Wiebe, M. E.; Rubin, B. Y. Identification of interferon-γ as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J. Exp. Med. 158: 670-689, 1983.
5. Zohlnhofer, D.; Richter, T.; Neumann, F.-J.; Nuhrenberg, T.; Wessely, R.; Brandl, R.; Murr, A.; Klein, C. A.; Baeuerle, P. A. Transcriptome analysis reveals a role of interferon-γ in human neointima formation. Molec. Cell 7: 1059-1069, 2001

       1. Awad, M.; Pravica, V.; Perrey, C.; El Gamel, A.; Yonan, N.; Sinnott, P. J.; Hutchinson, I. V. CA repeat allele polymorphism in the first intron of the human interferon-γ gene is associated with lung allograft fibrosis. Hum.Immunol. 60: 343-346, 1999.


       2. Szabo, S. J.; Sullivan, B. M.; Stemmann, C.; Satoskar, A. R.; Sleckman, B. P.; Glimcher, L. H. Distinct effects of T-bet in T(H)1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science 295: 338-342, 2002.

       3. Rossouw, M.; Nel, H. J.; Cooke, G. S.; van Helden, P. D.; Hoal, E. G. Association between tuberculosis and a polymorphic NF-kappa-B binding site in the interferon gamma gene. Lancet 361: 1871-1872, 2003.


       4. Nathan, C. F.; Murray, H. W.; Wiebe, M. E.; Rubin, B. Y. Identification of interferon-γ as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J. Exp. Med. 158: 670-689, 1983.


       5. Zohlnhofer, D.; Richter, T.; Neumann, F.-J.; Nuhrenberg, T.; Wessely, R.; Brandl, R.; Murr, A.; Klein, C. A.; Baeuerle, P. A. Transcriptome analysis reveals a role of interferon-γ in human neointima formation. Molec. Cell 7: 1059-1069, 2001
There are no product questions yet.
公司简介 / Company profile
上海中乔新舟生物科技有限公司
Shanghai Zhong Qiao Xin Zhou Biotechnology Co.,Ltd.
           上海中乔新舟生物科技有限公司(官网:www.zqxzbio.com)成立于2011年,历经...
联系我们 / Contact
电 话:021-56760357;021-56760351
传 真:
邮 箱:sales@zqxzbio.com
邮 编:200439
地 址:上海市宝山区长江南路180号
Copyright © 2014 ZQXZBIO All rights reserved.
技术支持:中乔新舟沪ICP备14008091号