欢迎您访问中乔新舟官网!400-038-9959我的购物车(0)
您当前的位置:首页 > 产品中心
小鼠钙粘着蛋白ELISA试剂盒
英文名:Mouse E-Cadherin ELISA Kit
货号:EK0562
价格:¥7560.00
加入购物车,提交订单信息之后,我们会第一时间与您取得联系!
  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

小鼠钙粘着蛋白ELISA试剂盒描述:



       E-Cadherin is also called Cadherin 1(CDH1) or calcium-dependent adhesion protein, epithelial. E-cadherin is a Ca2+-dependent epithelial cell-cell adhesion molecule. Downregulation of E-cadherin expression often correlates with strong invasive potential and poor prognosis of human carcinomas. The gene spans a region of approximately 100 kb, and is located on chromosome 16q22.1. It contains 16 exons and a 65kb-long intron 2. Mutations in E-cadherin may contribute to the development of diffusely growing gastric carcinomas. E-cadherin plays a central part in the process of epithelial morphogenesis and acts as a strong invasion suppressor in experimental tumor cell systems. The standard product used in this kit is recombinant E-Cadherin with a molecular mass of 120kDa. ScienCell's human E-Cadherin ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Human E-Cadherin-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The human specific detection polyclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes into yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of mouse E-Cadherin in the sample that is captured on the strips.


产品使用说明:仅供科研研究使用

货号

EK0562

产地

美国

缩写

mECad-ELISA

规格

96 tests

用途

科研

保存

频繁使用存储在4°C,很少使用存储在-20°C

运输

胶冰

参考文献

1. Berx, G.; Staes, K.; van Hengel, J.; Molemans,F.; Bussemakers, M. J. G.; van Bokhoven, A.; van Roy,F. : Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). Genomics 26: 281-289, 1995.
2. Becker, K.-F.; Atkinson, M. J.; Reich, U.; Becker, I.; Nekarda, H.; Siewert, J. R.; Hoefler, H. : E-Cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res. 54: 3845-3852, 1994.
3. Batlle, E.; Sancho, E.;Franci, C.; Dominguez, D.; Monfar, M.; Baulida, J.; Garcia de Herreros, A. : The transitionFactor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nature Cell Biol. 2: 84-89, 2000.

       1. Berx, G.; Staes, K.; van Hengel, J.; Molemans,F.; Bussemakers, M. J. G.; van Bokhoven, A.; van Roy,F. : Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). Genomics 26: 281-289, 1995.


       2. Becker, K.-F.; Atkinson, M. J.; Reich, U.; Becker, I.; Nekarda, H.; Siewert, J. R.; Hoefler, H. : E-Cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res. 54: 3845-3852, 1994.


       3. Batlle, E.; Sancho, E.;Franci, C.; Dominguez, D.; Monfar, M.; Baulida, J.; Garcia de Herreros, A. : The transitionFactor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nature Cell Biol. 2: 84-89, 2000.

There are no product questions yet.
公司简介 / Company profile
上海中乔新舟生物科技有限公司
Shanghai Zhong Qiao Xin Zhou Biotechnology Co.,Ltd.
           上海中乔新舟生物科技有限公司(官网:www.zqxzbio.com)成立于2011年,历经...
联系我们 / Contact
电 话:021-56760357;021-56760351
传 真:
邮 箱:sales@zqxzbio.com
邮 编:200439
地 址:上海市宝山区长江南路180号
Copyright © 2014 ZQXZBIO All rights reserved.
技术支持:中乔新舟沪ICP备14008091号