人肝星形细胞说明：
肝脏星形细胞是小叶内结缔组织细胞，呈现肌成纤维细胞样或脂肪细胞形态。他们参与肝脏细胞外基质的稳态、修复、再生、纤维化以控制视黄醇的代谢、存储和释放。肝脏受伤后，肝脏星形细胞转化成肌成纤维细胞，并且是纤维化的肝脏中I 型胶原的主要来源。除了以上特征，已发现在疾病状态和肝内门静脉高压的发病过程中，肝星状细胞通过细胞收缩调节肝脏微循环、星形细胞的增殖、迁移和趋化因子的表达参与了肝脏炎症和纤维化的发病过程。星形细胞支配电压激活的钙离子流，表达低亲和力的神经生长因子受体p75，在神经生长因子的刺激下发生细胞凋亡。因此，星形细胞激活的分子调控在将来有助于治疗纤维化肝，并且能减少慢性肝病患者的发病率和死亡率。
人肝脏星形细胞(HHSteC)提取于人肝脏组织，原代冻存。每管含有细胞数>5×105cells/ml，此细胞通过对Desmin, alpha-Actin和Fibronectin免疫荧光染色验证，经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。
配套培养基: 星形细胞培养基(SCM, Cat. No. 5301)
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