人卵巢表层上皮细胞HOSEpiC

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人卵巢表层上皮细胞

英文名：Human Ovarian Surface Epithelial Cells
货号：7310
价格：￥15390.00

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人卵巢表层上皮细胞说明：

卵巢被单一覆盖层的表层上皮细胞所覆盖，这层细胞在体内的形态由鳞状上皮变化成低柱状立方形。OSEpiC参与周期性排卵卵泡破裂和随后的修复。OSEpiC表达大量的多肽类激素，性激素，生长因子和受体。这些众多的生物物质与卵巢上皮癌和性传播疾病的发生发展有关。研究相应细胞通路的畸变可以了解OSEpiC的生长、凋亡、转化和在疾病发生时的功能及潜在的标记物质，这些可以为临床治疗疾病提供非常重要的信息。

Sciencell研究实验室的HOSEC是从人卵巢分离提取，属第一代冻存，干冰冰冻运输。每管细胞密度5×10^5/ml。细胞特性经cytokeratine-14, -18, and -19免疫荧光鉴定。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell 实验室特制的培养基，可保证此细胞5倍增增殖。

配套培养基：卵巢上皮细胞培养基 (OEpiCM, Cat No 7311)

产品使用说明：仅供科研研究使用

货号	7310
产地	美国
缩写	HOSEpiC
规格	5 x 10^5 cells/vial
用途	科研
运输	干冰
保存	液氮

1.) Halabi, N.M., Martinez, A., Al-Farsi, H., Mery, E., Puydenus, L., Pujol, P., Khalak, H.G., McLurcan, C., Ferron, G., Querleu, D., Al-Azwani, I., Al-Dous, E., Mohamoud, Y.A., Malek, J.A. & Rafii, A. (2016) Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer PLoS Genet. 12

2.) Lang, F., Qin, Z., Li, F., Zhang, H., Fang, Z. & Hao, E. (2015) Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells PLoS One. 10

3.) Ibrahim, F.F., Jamal, R., Syafruddin, S.E., Ab Mutalib, N.S., Saidin, S., MdZin, R.R., Hossain Mollah, M.M. & Mokhtar, N.M. (2015) MicroRNA-200c and microRNA-31 regulate proliferation, colony formation, migration and invasion in serous ovarian cancer J Ovarian Res. 8

4.) Barger, C.J., Zhang, W., Hillman, J., Stablewski, A.B., Higgins, M.J., Vanderhyden, B.C., Odunsi, K. & Karpf, A.R. (2015) Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression Oncotarget. 6

5.) Semaan A, Qazi AM, Seward S, Chamala S, Bryant CS, Kumar S, Morris R, Steffes CP, Bouwman DL, Mukarah AR, Weaver DW, Gruber SA, Batchu RB. (2011) "MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21waf1/cip1." Pharm Res. 28: 3079-90.

6.) Selvendiran K, Ahmed S, Dayton A, Kuppusamy ML, Tazi M, Bratasz A, Tong L, Rivera BK, K?lai T, Hideg K, Kuppusamy P. (2010) "Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells." Free Radic Biol Med. 48: 1228-35.

7.) Selvendiran K, Tong L, Bratasz A, Kuppusamy ML, Ahmed S, Ravi Y, Trigg NJ, Rivera BK, K?lai T, Hideg K, Kuppusamy P. (2010) "Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts." Mol Cancer Ther. 9: 1169-79.

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