产品名称 |
OCI-Aml-3人急性髓性白血病细胞 |
货号 |
ZQ0580 |
产品介绍 |
OCI-Aml-3是一种人急性髓性白血病细胞系,是从1987年诊断为急性髓细胞性白血病(AML FAB M4)的57岁男性的外周血中建立的。细胞携带NPM1基因突变(A型)和DNMT3A R882C突变。广泛用于急性髓性白血病的研究,包括药物筛选、细胞信号传导研究、白血病的分子机制研究等。例如:OCI-Aml-3细胞系在药物筛选中的应用主要包括以下几个方面:白血病药物靶点的鉴定、药物敏感性测试、药物组合效应研究、药物耐药性研究、药物开发和前临床研究、药物作用机制研究等。这些应用展示了OCI-Aml-3细胞系在AML药物筛选和研究中的广泛价值,为开发新的治疗策略和药物提供了重要的实验工具。 |
种属 |
人 |
性别/年龄 |
男/57岁 |
组织 |
外周血 |
疾病 |
急性髓性白血病 |
细胞类型 |
肿瘤细胞 |
形态学 |
单个,主要是圆形细胞 |
生长方式 |
悬浮 |
倍增时间 |
大约28~40小时 |
培养基和添加剂 |
RPMI-1640基础培养基(中乔新舟 货号:ZQ-200)+20%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin:X; |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
DSMZ; ACC-582 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0580 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
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