产品名称 |
CAL 27人舌鳞状细胞癌细胞 |
货号 |
ZQ0606 |
产品介绍 |
CAL 27是一种人舌鳞状细胞癌细胞系,源自1982年由J. Gioanni(法国尼斯塞德市安托万·拉卡塞格内中心)从一位56岁男性舌头上的原发肿瘤组织中建系,该患者患有舌中部病变。 细胞具有高密度颗粒状胞浆和上皮细胞样的形态,贴壁生长。具有高侵袭性和转移能力,对某些药物敏感,但对其他一些药物如VP16、CCNU、VM26、ADM、CPA和MTX表现出耐药性。被广泛用于科学研究,以研究口腔致癌作用、鳞状细胞和口咽癌的生物学,以及评估头颈癌的潜在治疗药物。
CAL 27细胞已在多种研究应用中得到使用,包括细胞增殖、凋亡的研究,特别是在抗癌药物敏感性和寻找新型抗癌药物的背景下,以及迁移和侵袭的研究。它们还被用于研究各种化疗药物如顺铂、放射疗法和靶向疗法的效果。 |
种属 |
人 |
性别/年龄 |
男/56岁 |
组织 |
舌头 |
疾病 |
鳞状细胞癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
上皮的 |
生长方式 |
贴壁 |
倍增时间 |
大约20~45小时 |
培养基和添加剂 |
MEM(含NEAA)(中乔新舟 货号:ZQ-300)+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X
D3S1358: 16
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; CRL-2095 BCRJ; 0326 DSMZ; ACC-446 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0606 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: YKT6, as a potential predictor of prognosis and immunotherapy response for oral squamous cell carcinoma, is related to cell invasion, metastasis, and CD8+ T cell infiltration
DOI: 10.1080/2162402X.2021.1938890
发表时间: 2021-06-23
期刊: OncoImmunology
影响因子: 8.11
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/2162402X.2021.1938890
论文标题: Genetic variants associated with expression of TCF19 contribute to the risk of head and neck cancer in Chinese population
DOI: 10.1136/jmedgenet-2020-107410
发表时间: 2022-04-01
期刊: JOURNAL OF MEDICAL GENETICS
影响因子: 5.941
货号: ZQ0606
产品名称: CAL27 cells
原文链接: https://jmg.bmj.com/content/59/4/335.abstract
论文标题: Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway
DOI: 10.1111/cas.14362
发表时间: 2020-03-18
期刊: CANCER SCIENCE
影响因子: 4.966
货号: ZQ0606
产品名称: CAL27 OSCC cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7226219/
论文标题: ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2
DOI: 10.7150/jca.63919
发表时间: 2021-10-25
期刊: Journal of Cancer
影响因子: 4.207
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8734408/
论文标题: Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells
DOI: 10.2147/OTT.S174637
发表时间: 2018-11-13
期刊: OncoTargets and Therapy
影响因子: 4.147
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239101/
论文标题: MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells
DOI: 10.1155/2021/6650791
发表时间: 2021-06-04
期刊: Biomed Research International
影响因子: 3.411
货号: ZQ0606
产品名称: CAL 27 cells
原文链接: https://www.hindawi.com/journals/bmri/2021/6650791/
论文标题: Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway
DOI: 10.1155/2021/6616547
发表时间: 2021-06-10
期刊: Biomed Research International
影响因子: 3.411
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.hindawi.com/journals/bmri/2021/6616547/
论文标题: Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter
DOI: 10.1080/21655979.2021.2012951
发表时间: 2021-12-29
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.2012951
论文标题: Zinc‑finger protein 750 mitigates malignant biological behavior of oral CSC‑like cells enriched from parental CAL‑27 cells
DOI: 10.3892/ol.2021.13146
发表时间: 2021-11-19
期刊: Oncology Letters
影响因子: 2.967
货号: ZQ0606
产品名称: CAL-27 cells
原文链接: https://www.spandidos-publications.com/10.3892/ol.2021.13146
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