产品名称 |
NCI-H2126人肺癌细胞 |
货号 |
ZQ0703 |
产品介绍 |
NCI-H2126是一种人非小细胞肺癌(NSCLC)细胞系,源自一位65岁白人男性患者的胸腔积液,该患者患有肺腺癌。这个细胞系在癌症研究中非常有用,尤其是在研究肺癌的生物学特性和药物筛选方面。来自同一患者的 EBV 转化的淋巴母细胞系可作为 ATCC CCL-256.1 获得。 |
种属 |
人 |
性别/年龄 |
男/65岁 |
组织 |
肺;来源于胸腔积液转移灶 |
疾病 |
腺癌;非小细胞肺癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
上皮的 |
生长方式 |
贴壁 |
倍增时间 |
大约41.1~57小时 |
培养基和添加剂 |
RPMI-1640(品牌:中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006)+1% Sodium Pyruvate 100 mM Solution(中乔新舟 货号:CSP003)+1%L-alanyl-L-glutamine(中乔新舟 货号:CSP004) |
推荐完全培养基货号 |
ZM0703 |
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; CCL-256 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0703 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
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Mitsudomi T., Steinberg S.M., Nau M.M., Carbone D.P., D'Amico D., Bodner S.M., Oie H.K., Linnoila R.I., Mulshine J.L., Minna J.D., Gazdar A.F.
p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.
Oncogene 7:171-180(1992)
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NCI-Navy Medical Oncology Branch cell line data base.
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Virmani A.K., Fong K.M., Kodagoda D.R., McIntire D., Hung J., Tonk V., Minna J.D., Gazdar A.F.
Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types.
Genes Chromosomes Cancer 21:308-319(1998)
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Girard L., Zochbauer-Muller S., Virmani A.K., Gazdar A.F., Minna J.D.
Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering.
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Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
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PubMed=11416159; DOI=10.1073/pnas.121616198
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Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)
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Bignell G.R., Huang J., Greshock J., Watt S., Butler A.P., West S., Grigorova M., Jones K.W., Wei W., Stratton M.R., Futreal P.A., Weber B., Shapero M.H., Wooster R.
High-resolution analysis of DNA copy number using oligonucleotide microarrays.
Genome Res. 14:287-295(2004)
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Grigorova M., Lyman R.C., Caldas C., Edwards P.A.W.
Chromosome abnormalities in 10 lung cancer cell lines of the NCI-H series analyzed with spectral karyotyping.
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PubMed=19153074; DOI=10.1093/hmg/ddp034
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The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.
Hum. Mol. Genet. 18:1343-1352(2009)
PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)
PubMed=20164919; DOI=10.1038/nature08768
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Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)
PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)
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Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
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产品名称 | 价格 | 指令 |
95-D [PLA-801D]人肺癌细胞(高转)[套餐促销] | ¥1350.00 | 购物车 》 |
NCI-H1755人肺癌细胞(STR鉴定) | ¥1900.00 | 购物车 》 |
NCI-H838人肺癌细胞(STR鉴定) | ¥1600.00 | 购物车 》 |
NCI-H1703人肺鳞癌细胞(STR鉴定) | ¥1350.00 | 购物车 》 |
NCI-H226人肺鳞癌细胞(STR鉴定) | ¥1350.00 | 购物车 》 |
NCI-H460人肺癌细胞(STR鉴定) | ¥1350.00 | 购物车 》 |
NCI-H292人肺癌细胞(淋巴结转移) (STR鉴定) | ¥1350.00 | 购物车 》 |