产品名称 |
Hcc1806人乳腺癌细胞 |
货号 |
ZQ0769 |
产品介绍 |
HCC1806是一种人乳腺癌细胞系,源自一位60岁黑人女性的乳腺鳞状细胞癌(ASCC),TNM分期为IIB期,分级为2级。该细胞系于1995年7月31日建立,历时10个月。该细胞缺乏雌激素和黄体酮受体,并且缺乏表皮生长因子受体(EGFR)扩增,将其归类为三阴性乳腺癌。该细胞系有助于治疗靶点的生物学验证,因为它密切反映了TNBC在体内的行为,包括自发转移的倾向和对紫杉醇等传统疗法的耐药性。此外,干预的分子效应如AEB071治疗,对HCC1806细胞,提供了细胞增殖途径和蛋白激酶抑制剂作为治疗药物的潜力。在异种移植物模型中使用HCC1806有助于在受控环境下研究肿瘤的生长和转移。 |
种属 |
人 |
性别/年龄 |
女/60岁 |
组织 |
乳房;乳腺 |
疾病 |
棘层溶解性鳞状细胞癌;TNM舞台IIB,二级 |
细胞类型 |
上皮细胞 |
形态学 |
上皮的 |
生长方式 |
贴壁、附着的中等大小上皮细胞,无漂浮细胞 |
倍增时间 |
大约36.66小时 |
培养基和添加剂 |
RPMI-1640(品牌:中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
D5S818: 13Amelogenin:X |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; CRL-2335 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0769 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
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