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A2780人卵巢癌细胞
英文名:A2780
货号:ZQ0486
价格:¥1350.00
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推荐组合

A2780人卵巢癌细胞

¥1350.00
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A2780人卵巢癌细胞专用培养基

¥350.00 ¥480.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥1700 ¥2680.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

A2780人卵巢癌细胞

货号

ZQ0486

产品介绍

A2780细胞系最初是从ECACC获得的,其细胞形态为上皮细胞样,生长特性为贴壁生长。该细胞被分离自一名未经治疗的卵巢癌患者的肿瘤组织,在建立过程中未受到抗癌药物或化学物质的影响。在支原体检测中呈阴性。
A2780细胞系以单层和悬浮液的形式在旋转培养器中生长,被广泛应用于毒性试验和癌症基因研究。此外该细胞系已被用于多项研究,包括探索蜗牛和蛞蝓在卵巢肿瘤新生血管形成中的作用,以及应用脂质体克服卵巢癌细胞对顺铂的耐药性的研究。研究也证实了NMDA(N-甲基-D-天冬氨酸)受体作为治疗卵巢癌的潜在靶点的意义,以及低分子肝素对卵巢癌细胞顺铂耐药性的影响。
A2780细胞在癌症治疗和耐药机制研究中被广泛应用。由于其来自未经治疗的患者,A2780细胞系成为了评估癌症治疗效果、研究治疗耐药性以及探索新药物疗法的重要模型之一。

A2780细胞的亲本株A2780还衍生出顺铂耐药细胞系A2780 cis和阿霉素耐药细胞系A2780 ADR,为进一步研究耐药机制提供了有力工具。

种属

性别/年龄

组织

卵巢

疾病

卵巢子宫内膜样腺癌 

细胞类型

肿瘤细胞 

形态学

上皮的

生长方式

贴壁和悬浮,混合生长

倍增时间

大约16~26.3小时

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200)+2 mM L-谷氨酰胺(中乔新舟 货号:CSP012)+1 mM 丙酮酸钠(中乔新舟 货号:CSP003)+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%双抗(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0486

生物安全等级

BSL-1

STR位点信息

Amelogenin:X
CSF1PO: 10,11
D2S1338:21,22
D3S1358:14,16
D5S818: 11,12
D7S820: 10
D8S1179:15,17
D13S317:12,13
D16S539:11,12,13 (ICLC=HTL98008)
                11,13 (AddexBio=C0017002/20; Cosmic-CLP=906804;                                                 ECACC=93112519; PubMed=25230021; PubMed=25877200;                               PubMed=30485824)
D18S51: 16,18
D19S433:12
D21S11: 28 (PubMed=25230021; PubMed=25877200)
               28,29 (PubMed=30485824)
FGA:19,24
Penta D: 8,9
Penta E: 10,13
TH01:6
TPOX:8,10
vWA:15,16。 

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ECACC; 93112519

供应限制

仅供科研使用


货号

ZQ0486

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


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