产品名称 |
Capan-2人胰腺癌细胞 |
货号 |
ZQ0923 |
产品介绍 |
Capan-2是一种人胰腺癌细胞系,起源于1975年从一位56岁白人男性胰腺癌患者的胰腺组织中分离出来。它源自肝脏的转移部位,表明其起源于继发性肿瘤,这使得它对于转移过程和胰腺癌生物学的研究特别有价值。这些细胞表现出上皮形态,并已广泛用于研究胰腺癌、耐药性和肿瘤生物学。这种细胞系具有多边形形态,属于假三倍体,其主要染色体数模态为69,但也存在范围在65至74之间的变异 。
Capan-2 细胞已知表达 Kirsten 大鼠肉瘤病毒癌基因同源物 (KRAS) 的突变形式,这是胰腺癌中的常见突变,这使它们成为研究 KRAS 驱动的肿瘤发生的强大模型。此外,它们的特征是肿瘤抑制基因 p53 突变的表达,并观察到表现出染色体不稳定性,这是与癌症进展和治疗反应相关的关键特征。该细胞系已用于许多研究,包括评估化疗效果、探索癌症进展的分子途径以及开发靶向治疗策略。 注意事项:
(1)capan-2 细胞呈块片状聚集生长,细胞胞体黑点较多是正常现象。 |
种属 |
人 |
性别/年龄 |
男/56岁 |
组织 |
胰腺 |
疾病 |
腺癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
多边形上皮样, 贴壁生长 |
生长方式 |
贴壁 |
倍增时间 |
大约120~168小时 |
培养基和添加剂 |
RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X
CSF1PO: 11,12
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; HTB-80 BCRJ; 0060 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0923 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
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