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OCI-AML-2人急性髓系白血病(STR鉴定)
英文名:OCI-AML-2
货号:ZQ0919
价格:¥1500.00
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推荐组合

OCI-AML-2人急性髓系白血病(STR鉴定)

¥1500.00
+

OCI-Aml-2人急性髓系白血病专用培养基

¥650.00

配套完培,省时省力,单买细胞无优惠

=

细胞套餐惊爆价

¥2150
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

OCI-AML2人急性髓系白血病

货号

ZQ0919

产品介绍

1986年诊断为急性髓系白血病(AML-FAB M4)的65岁男性患者外周血建立;文献中描述了表达维甲酸受体基因的细胞;细胞系携带DNMT3A R635W突变。OCI-AML-2细胞系可用于白血病的研究、药物筛选、细胞治疗等领域的实验研究。

种属

性别/年龄

/65岁

组织

胰腺

疾病

急性髓性白血病

细胞类型

肿瘤细胞

形态学

单细胞,圆形至椭圆形悬浮细胞

生长方式

悬浮

倍增时间

30 hours (PubMed=25984343); ~30-50 hours (DSMZ=ACC-99)

培养基和添加剂

MEM α 基础培养基(中乔新舟  货号:ZQ-800+20%胎牛血清(中乔新舟 货号:ZQ0500+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0919

生物安全等级

BSL-1

STR位点信息

Amelogenin:X,Y
CSF1PO: 10,12
D2S1338:23,25
D3S1358:16
D5S818: 12
D7S820: 12
D8S1179:12,15
D13S317:11,12
D16S539:12,13
D18S51: 14
D19S433:13,14
D21S11: 29
FGA:19,24
Penta D: 12
Penta E: 12,14
TH01:6,9.3
TPOX:11
vWA:14,17

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

BCRJ; 0383 DSMZ; ACC-99 

供应限制

仅供科研使用


货号

ZQ0919

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


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Nature 463:893-898(2010)


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Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
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PubMed=25984343; DOI=10.1038/sdata.2014.35
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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)


PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)


PubMed=25877200; DOI=10.1038/nature14397
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A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)


PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)


PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
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PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
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PubMed=30629668; DOI=10.1371/journal.pone.0210404
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Screening human cell lines for viral infections applying RNA-Seq data analysis.
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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PubMed=30971826; DOI=10.1038/s41586-019-1103-9
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
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