小神经胶质细胞存在于中枢神经系统内,是中枢神经系统一个重要的有机组成部分[1]。小神经胶质细胞作为在大脑发育或中枢神经系统受伤或病态损坏时的监控细胞。小神经胶质细胞可以被认为是大脑的主要细胞免疫监视,可呈现抗原分子MHC II级表达式的上下文的cd - 4积极的T细胞,能够被Fc-mediated吞噬,并激活许多共同抗原和造血组织巨噬细胞[2]。小神经胶质细胞在中枢神经系统中扮演着一个重要的角色。此外,有越来越多的证据表明，小神经胶质细胞通过与其他神经元和神经胶质细胞和产生生物活性物质如生长因子、细胞因子、和其他因素[3]，参与在大脑中的多种生理和病理过程。

        ScienCell实验室的HM提取自大脑皮层，原代冻存，冰冻运输。每管细胞密度超过1×106/ml。细胞经OX-42（CD11b/c）和F4/80免疫荧光鉴定。本细胞经检测不含HIV-1, HBV, HCV, 支原体, 细菌, 酵母菌和真菌。如采用ScienCell 实验室特制的培养基，可保证此细胞生长良好。HM不推荐增值培养。   

配套培养基：神经胶质细胞培养基(货号：1901)

产品使用说明：仅供科研研究使用

Question:1

Dear whom it may concern, I’m wondering whether your microglia express chemokine receptors particularly, CD36, TLR3, TLR4, TLR7. Any finding by you or your customers are valuable for me to use your cells as the model. Thanks, H.Cho
Answers:
Posted by Manoj Sharma on Monday, January 18, 2016
We do not test for the receptors listed.  
Thank you for your interest in ScienCell products

Question:2
Hello, Do these human microglia immortalized cells express CD80/86 as normal microglia do when stimulated? Also, are there any publications that utilized this cell line for flow cytometryic analysis? Thanks
Answers:
Posted by Manoj Sharma on Thursday, January 7, 2016
Hi Leo,
Human microglia provided by ScienCell are primary cells, not immortalized cell lines.
Thank you for your interest
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