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HuP-T4人胰腺癌细胞 (STR鉴定)
英文名:HuP-T4
货号:ZQ0772
价格:¥4800.00
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推荐组合

HuP-T4人胰腺癌细胞 (STR鉴定)

¥4800.00
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HuP-T4人胰腺癌细胞专用培养基

¥500.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥5300
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

HuP-T4人胰腺癌细胞

货号

ZQ0772

产品介绍

这株细胞是在1985年在一名60岁胰腺癌患者的恶性腹水中发现的。被广泛用于胰腺癌的研究,包括药物筛选、癌症生物学特性研究等。以下是HuP-T4细胞系在胰腺癌研究中的一些具体应用:药物筛选、癌症生物学特性研究、基因和信号通路研究、肿瘤微环境研究、癌症基因组学研究、类器官模型构建、细胞Panel筛选、免疫治疗研究等。这些应用展示了HuP-T4细胞系在胰腺癌研究中的多样性和重要性,为理解胰腺癌的复杂性提供了重要的实验模型。

种属

性别/年龄

/60岁

组织

胰腺

疾病

胰腺癌

细胞类型

肿瘤细胞

形态学

上皮的

生长方式

贴壁

倍增时间

 ~38 hours (DSMZ=ACC-223)

培养基和添加剂

MEM(品牌:中乔新舟 货号:ZQ-300)+20%胎牛血清(中乔新舟 货号:ZQ0500+1%P/S(中乔新舟  货号:CSP006+1%NEAA(中乔新舟 货号:CSP008+1%Sodium pyruvate(中乔新舟  货号:CSP003

推荐完全培养基货号

ZM0772

生物安全等级

BSL-2

STR位点信息

Amelogenin: X

CSF1PO 10,12

D2S1338 18,19

D3S1358 15

D5S818 10,11

D7S820 8,11

D8S1179 11,16

D13S317 8 (DSMZ=ACC-223)

                 :8,9 (Cosmic-CLP=907286; ECACC=93121056;                        PubMed=25877200)

D16S539 10,11

D18S51 18

D19S433 13

D21S11 29,32.2

FGA 23,24,25

Penta D 9

Penta E 18,19

TH01 9

TPOX 8

vWA 17,18

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

DSMZ; ACC-223;ECACC; 93121056;ICLC; HTL95006

供应限制

仅供科研使用


货号 

ZQ0772

发货规格 

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 

发货形式 

活细胞:常温运输;冻存管:干冰运输 

储存温度 

活细胞:培养箱;冻存管:液氮罐 

产地 

中国 

供应限制 

仅供科研使用 

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)


DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
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PubMed=25167228; DOI=10.1038/bjc.2014.475
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KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition.
Br. J. Cancer 111:1788-1801(2014)


PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
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PubMed=25877200; DOI=10.1038/nature14397
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A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)


PubMed=26216984; DOI=10.1073/pnas.1501605112
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Proc. Natl. Acad. Sci. U.S.A. 112:E4410-E4417(2015)


PubMed=26589293; DOI=10.1186/s13073-015-0240-5
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Genome Med. 7:118.1-118.7(2015)


PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
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PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051
Yuan T.L., Amzallag A., Bagni R., Yi M., Afghani S., Burgan W., Fer N., Strathern L.A., Powell K., Smith B., Waters A.M., Drubin D.A., Thomson T., Liao R., Greninger P., Stein G.T., Murchie E., Cortez E., Egan R.K., Procter L., Bess M., Cheng K.T., Lee C.-S., Lee L.C., Fellmann C., Stephens R., Luo J., Lowe S.W., Benes C.H., McCormick F.
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
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