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OPM-2 人多发性骨髓瘤细胞 (STR鉴定)
英文名:OPM-2 human multiple myeloma cells
货号:ZQ1025
价格:¥8450.00
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OPM-2 人多发性骨髓瘤细胞 (STR鉴定)

¥8450.00
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OPM-2人多发性骨髓瘤细胞专用培养基

¥350.00 ¥500.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥8800 ¥8950.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

OPM-2 人多发性骨髓瘤细胞

货号

ZQ1025

产品介绍

OPM-2 细胞系于 1982 年建立,源自一名 56 岁女性的外周血,该女性被诊断患有 IgG lambda 亚型多发性骨髓瘤。在建立细胞系时,患者正处于疾病的白血病期,该阶段的特征是终末期复发。

OPM-2细胞系被广泛用于药物筛选、免疫学研究、细胞信号传导研究等领域。特别是在新药筛选研究中,用于评估不同药物对多发性骨髓瘤细胞的影响,研究肿瘤干细胞对化疗药物的敏感性。因其独特的特性和功能,在多发性骨髓瘤的研究中扮演着重要角色,为理解该疾病的发病机制和开发新的治疗方法提供了重要的实验工具。 

种属

性别/年龄

/56岁

组织

外周血

疾病

多发性骨髓瘤

细胞类型

肿瘤细胞

形态学

上皮

生长方式

悬浮

倍增时间

 50-60小时

培养基和添加剂

RPMI-1640(品牌:中乔新舟 货号:ZQ-200+10%FBS(货号:ZQ500-A+1%PS(货号:CSP006

推荐完全培养基货号

ZM1025

生物安全等级

BSL-1

培养条件

95%空气,5%二氧化碳;37℃

STR位点信息

Amelogenin: X

CSF1PO 12,13

D1S1656 16,17.3

D2S441 10

D2S1338 19,25

D3S1358 15,18

D5S818 13

D7S820 12

D8S1179 10,13

D10S1248 14

D12S391 17,18

D13S317 11

D16S539 9,13

D18S51 13,14

D19S433 14,14.2 (Technion Genomics Center BCF)

               :14,15 (DSMZ=ACC-50)

D21S11 30,33.2

D22S1045 11,17

FGA 20,21

Penta D 9

Penta E 12,21

TH01 6,7

TPOX 8

vWA 14,17

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

DSMZ; ACC-50

供应限制

仅供科研使用


货号

ZQ1025

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用

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CLPUB00604

Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017), University of Toronto, Canada



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PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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Quantitative proteomics of the Cancer Cell Line Encyclopedia.
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PubMed=32123307; DOI=10.1038/s41375-020-0785-1
Sarin V., Yu K., Ferguson I.D., Gugliemini O., Nix M.A., Hann B., Sirota M., Wiita A.P.
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis.
Leukemia 34:2754-2765(2020)


PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

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