人牙龈成纤维细胞:
成纤维细胞是间叶细胞,它在成熟的生物体发育过程中具有许多重要的功能。成纤维细胞与结缔组织中细胞外基质的合成有关,并且在创伤愈合过程中起着重要作用。许多疾病都与成纤维细胞有关,不仅因为成纤维细胞与病原论有关,而且纤维症伴随着组织中其它细胞类型的损害。成纤维细胞是最易获得的哺乳动物细胞类型而且最适于体外培养。牙龈成纤维细胞是牙龈组织中的主要成分,并在维持牙龈健康中起着关键作用。人牙龈纤维原细胞表达广泛的表面分子,主要包括CD9, CD26, CD55, CD59, CD63, CD71, CD86 CD95, CD99和CD117。也有证据表明牙龈成纤维细胞为蛋白酶激活受体1和蛋白酶激活受体3表达mRNA。
人牙龈成纤维细胞(HGF)提取于人牙龈组织,原代冻存。每管含有细胞数>5×105 cells/ml,此细胞通过Fibronectin免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。
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