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产品名称 |
MV3 人黑色素瘤细胞 |
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货号 |
ZQ1082 |
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产品介绍 |
从患有下巴区域无色素原发性皮肤黑色素瘤(结节型，Clark IV)的76岁男性患者的淋巴小结转移中获得。在裸鼠身上易成瘤，表达转铁蛋白受体、表皮生长因子受体、ICAM-1、整合素α2β1。 |
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种属 |
人 |
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性别/年龄 |
男/76岁 |
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组织 |
淋巴结 |
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疾病 |
黑色素瘤 |
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细胞类型 |
肿瘤细胞 |
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形态学 |
成纤维样 |
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生长方式 |
贴壁 |
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倍增时间 |
~24 hours (PubMed=2019461) |
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培养基和添加剂 |
DMEM (中乔新舟 货号：ZQ-100)+10%胎牛血清（中乔新舟 货号：ZQ500-A）+1%P/S（中乔新舟 货号：CSP006） |
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推荐完全培养基货号 |
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生物安全等级 |
BSL-1 |
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培养条件 |
95%空气，5%二氧化碳；37℃ |
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STR位点信息 |
*** |
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抗原表达/受体表达 |
*** |
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基因表达 |
*** |
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保藏机构 |
BCRJ; 0284 |
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供应限制 |
仅供科研使用 |
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货号 |
ZQ1082 |
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发货规格 |
活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一 |
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发货形式 |
活细胞：常温运输；冻存管：干冰运输 |
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储存温度 |
活细胞：培养箱；冻存管：液氮罐 |
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产地 |
中国 |
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供应限制 |
仅供科研使用 |
PubMed=1918136; DOI=10.1083/jcb.115.1.191
Quax P.H.A., van Muijen G.N.P., Weening-Verhoeff E.J.D., Lund L.R., Dano K., Ruiter D.J., Verheijen J.H.
Metastatic behavior of human melanoma cell lines in nude mice correlates with urokinase-type plasminogen activator, its type-1 inhibitor, and urokinase-mediated matrix degradation.
J. Cell Biol. 115:191-199(1991)
PubMed=2019461; DOI=10.1002/ijc.2910480116
van Muijen G.N.P., Jansen K.F.J., Cornelissen I.L.M.H.A., Smeets D.F.C.M., Beck J.L.M., Ruiter D.J.
Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice.
Int. J. Cancer 48:85-91(1991)
PubMed=2060184; DOI=10.1007/BF01753729
van Muijen G.N.P., Cornelissen I.L.M.H.A., Jansen K.F.J., Figdor C.G., Johnson J.P., Brocker E.-B., Ruiter D.J.
Antigen expression of metastasizing and non-metastasizing human melanoma cells xenografted into nude mice.
Clin. Exp. Metastasis 9:259-272(1991)
PubMed=7646526; DOI=10.1006/bbrc.1995.2187
Artuc M., Nurnberg W., Czarnetzki B.M., Schadendorf D.
Characterization of gene regulatory elements for selective gene expression in human melanoma cells.
Biochem. Biophys. Res. Commun. 213:699-705(1995)
PubMed=8688321; DOI=10.1038/bjc.1996.337
Schadendorf D., Fichtner I., Makki A., Alijagic S., Kupper M., Mrowietz U., Henz B.M.
Metastatic potential of human melanoma cells in nude mice -- characterisation of phenotype, cytokine secretion and tumour-associated antigens.
Br. J. Cancer 74:194-199(1996)
PubMed=18235964; DOI=10.1590/S0100-879X2008005000003
Diego Geaquinto Leao A., Fernandes R.S., Lima L.G., Barja-Fidalgo C., de Queiroz Monteiro R.
Procoagulant properties of human MV3 melanoma cells.
Braz. J. Med. Biol. Res. 41:99-105(2008)
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