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A-427人肺癌细胞(STR鉴定)
英文名:A-427
货号:ZQ1111
价格:¥1500.00
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推荐组合

A-427人肺癌细胞(STR鉴定)

¥1500.00
+

A-427人肺癌细胞专用培养基

¥350.00 ¥450.00

配套完培,省时省力,单买细胞无优惠

=

细胞套餐惊爆价

¥1850 ¥1950.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

A-427人肺癌细胞

货号

ZQ1111

产品介绍

A-427是一种人肺腺癌细胞系,源自一位52岁白人男性的肺癌细胞,由Giard·D·J建立。这些细胞在癌症研究中被广泛使用,具有上皮形态并贴壁生长。尤其是在肺癌的生物学特性研究、药物筛选和病理机制研究方面。在第 60 代,A427 细胞显示出亚三倍体至超三倍体的核型。这意味着细胞具有异常的染色体,包括双着丝粒、微小着丝粒和大的亚端着丝粒标记。这种核型异常通常与癌细胞有关,并导致该细胞系具有独特的特征。 A427 细胞具有致瘤特性,因此当注射到裸鼠体内时,它们会形成肿瘤。


这些肿瘤类似于未分化腺癌,进一步强调了该细胞系在研究肺癌及其进展中的相关性。凭借其卓越的特性,A427 细胞可用于各种应用,特别是在癌症研究中。它们的上皮形态和肺起源使它们成为研究肺癌和相关疾病的理想模型。此外,A427 细胞非常适合 3D 细胞培养技术,为探索肺癌细胞的行为提供了更具生理相关性的环境。

种属

性别/年龄

男/52岁

组织

疾病

肺癌

细胞类型

肿瘤细胞

形态学

上皮

生长方式

贴壁

倍增时间

28 hours (Note=In RPMI 1640 + 10% FBS), 38 hours (Note=In ACL-3), 42 hours (Note=In ACL-3+BSA) (PubMed=3940644); 36.6 hours (PubMed=29681454); ~60-70 hours (DSMZ=ACC-234)

培养基和添加剂

MEM(含有NEAA)(品牌:中乔新舟 货号:ZQ-300+10%胎牛血清(中乔新舟  货号:ZQ500-A+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM1111

生物安全等级

BSL-1

培养条件

95%空气,5%二氧化碳;37℃

STR位点信息

Amelogenin :X,Y

CSF1PO 10,12

D2S1338 17

D3S1358 16

D5S818 12

D7S820 8,12

D8S1179 12,13

D13S317 11,12

D16S539 11,13

D18S51 12

D19S433 13,14

D21S11 31.2

FGA 18

Penta D 13

Penta E 15,17

TH01 9

TPOX 8,11

vWA 17

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC; CRL-7906ATCC; HTB-53 DSMZ; ACC-234

供应限制

仅供科研使用


货号

ZQ1111

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用

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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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