人结肠上皮细胞HCoEpiC

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人结肠上皮细胞

英文名：Human Colonic Epithelial Cells
货号：2950
价格：￥14328.00

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人结肠上皮细胞

结肠直肠是恶性和非恶性血液病中的主要器官。位于结肠粘膜表面的细胞形成了主要的机械屏障，用于分离机体内部与外部环境。除了上皮细胞在离子交换中的作用外，这些细胞还可作为膜免疫系统中的整体部件发挥作用。在体外，人结肠上皮细胞可产生T细胞抗体，而在体内，该细胞可被刺激表达II级HLA和细胞内黏附分子。它们也可针对改变的基因表达和成长特点产生许多细胞因子。另外，正常结肠上皮细胞也可表达α3, α5, α6, β1 和 β4整合蛋白。

Sciencell研究实验室的人结肠上皮细胞是从人结肠中分离得到的，一代冻存，冰冻运输。每管细胞密度超过5×10^5 ml。该细胞可通过CK-18和CK-19特异性抗体的免疫荧光鉴定。该细胞不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell 实验室特制的培养基，可保证此细胞10倍增值。

推荐使用培养基：结肠上皮细胞培养基(CoEpiCM, Cat.No. 2951)

产品使用说明：仅供科研研究使用

货号	2950
产地	美国
缩写	HCoEpiC
规格	5x10^5cells/vial
用途	科研
运输	干冰
保存	液氮

1.) Das, U.N. (2016) Inflammatory bowel disease as a disorder of an imbalance between pro- and anti-inflammatory molecules and deficiency of resolution bioactive lipidsLipids Health Dis. 15

2.) Tsai, C.C., Chuang, T.W., Chen, L.J., Niu, H.S., Chung, K.M., Cheng, J.T. & Lin, K.C. (2015) Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells World J Gastroenterol. 21

3.) Li, J., Zhou, J., Zhang, D., Song, Y., She, J. & Bai, C. (2015) Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury J Cell Mol Med. 19

4.) Hua H, Chen W, Shen L, Sheng Q, Teng L. (2013) 'Honokiol augments the anti-cancer effects of oxaliplatin in colon cancer cells.'

5.) Rabineau M, Kocgozlu L, Dujardin D, Senger B, Haikel Y, Voegel JC, Freund JN, Schaaf P, Lavalle P, Vautier D. (2013) 'Contribution of Soft Substrates to Malignancy and Tumor Suppression during Colon Cancer Cell Division.'

6.) Hua H, Chen W, Shen L, Sheng Q, Teng L. (2013) "Honokiol augments the anti-cancer effects of oxaliplatin in colon cancer cells." ActaBiochimBiophys Sin.45: 773-79.

7.) Rabineau M, Kocgozlu L, Dujardin D, Senger B, Haikel Y, Voegel JC, Freund JN, Schaaf P, Lavalle P, Vautier D. (2013) "Contribution of Soft Substrates to Malignancy and Tumor Suppression during Colon Cancer Cell Division." PloS One. 8: e78468.

Question1:
Can these cells be passaged? For how many passages?
Answers:
Posted by Karishma Shah on Thursday, June 16, 2016
Dear customer,
Our primary cells are based on population doublings not passages. #2950 are guaranteed to further culture for 10 population doublings.

Question2:
Hi, Was this cell drived from healthy colon? Regards, Halim
Answers:
Posted by Karishma Shah on Monday, September 21, 2015
Hi Halim,
Thanks for asking! All our cells are derived from healthy tissues. Thanks!

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