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Raji人Burkitts淋巴瘤细胞(STR鉴定)

英文名:Raji
货号:ZQ0084
价格:¥1400.00
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推荐组合

Raji人Burkitts淋巴瘤细胞(STR鉴定)

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Raji人Burkitt's淋巴瘤细胞专用培养基

¥350.00 ¥450.00

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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

Raji人Burkitts淋巴瘤细胞

货号

ZQ0084

产品介绍

Raji是一种人Burkitt's淋巴瘤细胞系,最初由R.J.V. Pulvertaft于1963年从一名11岁黑人男性左上颌骨Burkitt淋巴瘤中建立。Raji细胞系在免疫学研究中目前在:CAR-T细胞治疗研究、NK细胞免疫杀伤研究、B细胞信号传导研究、EBV相关研究、免疫逃逸机制研究、药物代谢动力学研究等得到应用。这些应用展示了Raji细胞系在免疫学研究中的多样性和重要性,它们为理解B细胞淋巴瘤的复杂性提供了宝贵的工具。 EBNA阳性。

注意事项:
(1)Raji细胞通常在悬浮中以不同大小的浮动簇生长。随着培养密度的增加,细胞簇可以变得非常大,尽管也可能存在一些单细胞。在这
个细胞系中,碎片是正常的。
(2)细胞浓度不应超过2-3 × 10^6个细胞/ml,应加入足够的培养基使细胞浓度降至3-5 × 10^5个活细胞/ml,并避免生长培养基过度酸化。

种属

性别/年龄

男/11岁

组织

淋巴母细胞

疾病

Burkitt淋巴瘤,EBV相关伯基特淋巴瘤(NCIt:C27694),伯基特淋巴瘤(ORDO:Orphanet_543)。

细胞类型

肿瘤细胞

形态学

淋巴母细胞

生长方式

悬浮

倍增时间

大约20~36小时 

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200+10%胎牛血清(中乔新舟 货号:ZQ0500+1%双抗(中乔新舟   货号:CSP006

推荐完全培养基货号

ZM0084

生物安全等级

BSL-2

STR位点信息

Amelogenin: X,Y

D3S1358: 15,16
TH01: 6,7
D21S11: 28,31
D18S51: 17
Penta_E: 5,13
D5S818: 10,13
D13S317: 13
D7S820: 10
D16S539: 8,11
CSF1PO: 10,12
Penta_D: 3.2,9
vWA: 16,19
D8S1179: 14,15
TPOX: 8,13
FGA: 19,27
D19S433: 14,14.2
D2S1338: 22

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC; CCL-86 ATCC; CRL-7936 DSMZ; ACC-319 ECACC; 85011429

供应限制

仅供科研使用

货号

ZQ0084

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


1、论文标题: Conditional control of chimeric antigen receptor T-cell activity through a destabilizing domain switch and its chemical ligand
DOI: 10.1016/j.jcyt.2021.07.014
发表时间: 2021-09-28
期刊: CYTOTHERAPY
影响因子: 5.414
货号: ZQ0084
产品名称: Raji cells

原文链接: https://www.sciencedirect.com/science/article/pii/S1465324921007489


2、论文标题: Preparation and evaluation of etoposide-loaded lipid-based nanosuspensions for high-dose treatment of lymphoma
DOI: 10.2217/nnm-2018-0502
发表时间: 2019-06-10
期刊: Nanomedicine
影响因子: 4.717
货号: ZQ0084
产品名称: Human Raji lymphoma cells
原文链接: https://www.futuremedicine.com/doi/abs/10.2217/nnm-2018-0334


3、论文标题: Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway
DOI: 10.3892/mmr.2020.11785
发表时间: 2020-12-15
期刊: Molecular Medicine Reports
影响因子: 2.1
货号: ZQ0084
产品名称: Raji cells
原文链接: https://www.spandidos-publications.com/10.3892/mmr.2020.11785



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High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.
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Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)


10、PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)


11、PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)


12、PubMed=27566572; DOI=10.18632/oncotarget.11524
Quentmeier H., Pommerenke C., Ammerpohl O., Geffers R., Hauer V., MacLeod R.A.F., Nagel S., Romani J., Rosati E., Rosen A., Uphoff C.C., Zaborski M., Drexler H.G.
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13、PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
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Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
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16、PubMed=30629668; DOI=10.1371/journal.pone.0210404
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Screening human cell lines for viral infections applying RNA-Seq data analysis.
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Pan-cancer proteomic map of 949 human cell lines.
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