产品名称	A2058人皮肤癌
货号	ZQ0115
产品介绍	A2058细胞‌是一种人黑色素瘤细胞系，该细胞系是从一名 43 岁男性恶性黑色素瘤患者的淋巴结转移中分离出来的。由于其高侵袭性，这些细胞可用作细胞侵袭相关蛋白的来源，例如胶原蛋白 IV 型胶原酶、金属蛋白酶-2 组织抑制剂和自分泌运动因子。 这些细胞具有上皮细胞样的形态，贴壁生长。可用于研究黑色素瘤的生物学特性，包括细胞的增殖、侵袭和转移。也适用于药物筛选，测试潜在的抗癌药物的效力和毒性。
种属	人
性别/年龄	男/43岁
组织	皮肤；来源于转移部位：淋巴结
疾病	无色素性黑色素瘤(NCIt:C3802)
生物安全等级	BSL-1
STR位点信息	Amelogenin ：X,Y CSF1PO： 10,11 D1S1656：：15,18.3 D2S441： 11.3,14 D2S1338：17,18 D3S1358：14,15 D5S818： 9,12 D7S820： 11 D8S1179：12,13 D10S1248：14,15 D12S391：22,23 D13S317：13,14 D16S539：9,13 D18S51： 13,15 D19S433：14 D21S11： 29,30.2 D22S1045：16,17,18 DYS391： 11 FGA：21,24 Penta D： 9,12 Penta E： 10,13 TH01：7,9 TPOX：8 vWA：14,18
细胞类型	肿瘤细胞
形态学	上皮细胞
生长方式	贴壁
倍增时间	大约27小时
培养基和添加剂	DMEM高糖（品牌：中乔新舟 货号：ZQ-100）+10%FBS（品牌：中乔新舟 货号：ZQ500-A）+1%双抗（品牌：中乔新舟 货号：CSP006）
推荐完全培养基货号	ZM0115
培养条件	空气95%；CO25%, 37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC;
供应限制	仅供科研使用

货号	ZQ0115
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

1、论文标题： Identification and validation of a ferroptosis-related gene signature for predicting survival in skin cutaneous melanoma
DOI： 10.1002/cam4.4706
发表时间： 2022-04-04
期刊： Cancer Medicine
影响因子： 4.452
货号： ZQ0115
产品名称： A2058 cells
原文链接： https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.4706

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6、PubMed=25984343; DOI=10.1038/sdata.2014.35
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7、PubMed=25485619; DOI=10.1038/nbt.3080
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8、PubMed=25877200; DOI=10.1038/nature14397
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9、PubMed=26589293; DOI=10.1186/s13073-015-0240-5
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10、PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
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11、PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
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12、PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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13、PubMed=30971826; DOI=10.1038/s41586-019-1103-9
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14、PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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15、PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

16、PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)