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ACHN人肾细胞腺癌细胞(STR鉴定)

英文名:ACHN
货号:ZQ0340
价格:¥1350.00
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推荐组合

ACHN人肾细胞腺癌细胞(STR鉴定)

¥1350.00
+

ACHN人肾细胞腺癌细胞专用培养基

¥350.00 ¥480.00

配套完培,组合使用,省时省力

=

细胞套餐惊爆价

¥1700 ¥2080.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

ACHN人肾细胞腺癌细胞

货号

ZQ0340

产品介绍

ACHN细胞系来源于一位22岁白人男性肾腺癌广泛转移的恶性胸腔积液。该细胞系于1979年11月建立,随后将癌细胞直接播种到含有Eagle's MEM和10% FBS的培养瓶中。在150天的时间里,细胞被维持并在体外传代。随后,将这些细胞皮下接种到裸鼠体内,在四周内形成可触及的局部侵袭性肿瘤。该细胞系具有致瘤性,在接种107个细胞的裸鼠中100%(5/5)诱导肿瘤,21天内肿瘤发生。
ACHN细胞的特点是贴壁生长模式和表达特异性同工酶,包括G6PD (B型)。该细胞系也因其对人类干扰素和干扰素诱导剂的反应而闻名,使其在抗增殖研究中特别有用。裸鼠原始ACHN细胞和从肿瘤中恢复的ACHN细胞在人类干扰素的存在下都表现出生长抑制,这突出了它们在探索干扰素治疗肾癌疗效的研究中的潜在应用。
ACHN 细胞系是癌症研究的重要工具,特别是在肾腺癌方面。它是研究致瘤性、转移行为以及干扰素对癌细胞增殖影响的重要模型。它在体内形成肿瘤并对干扰素治疗作出反应的能力为开发和测试针对肾细胞癌的新治疗方法提供了强大的平台。

【注意事项】该细胞生长受到人类干扰素抑制

种属

性别/年龄

男/22岁

组织

肾;来源于转移部位:胸腔积液

疾病

肾细胞腺癌

细胞类型

肿瘤细胞

形态学

上皮的

生长方式

贴壁

倍增时间

大约27.5~32小时 

培养基和添加剂

MEM(含有NEAA)基础培养基(品牌:中乔新舟 货号:ZQ-300)+10%FBS(品牌:中乔新舟 货号:ZQ500-A+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0340

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 11

D13S317: 12

D16S539: 12,13

D5S818: 12

D7S820: 9,11

TH01: 8

TPOX: 8,11

vWA: 16,17

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ATCC; CRL-1611 ECACC; 88100508

供应限制

仅供科研使用

货号

ZQ0340

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Triple-serotype chimeric oncolytic adenovirus exerts multiple synergistic mechanisms against solid tumors
DOI: 10.1136/jitc-2022-004691
发表时间: 2022-05-01
期刊: Journal for ImmunoTherapy of Cancer
影响因子: 13.751
货号: ZQ0340
产品名称: ACHN cells
原文链接: https://jitc.bmj.com/content/10/5/e004691.abstract


论文标题: Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma
DOI: 10.1016/j.prp.2021.153622
发表时间: 2021-09-20
期刊: PATHOLOGY RESEARCH AND PRACTICE
影响因子: 3.25
货号: ZQ0340
产品名称: ccRCC cell lines ACHN

原文链接: https://www.sciencedirect.com/science/article/pii/S0344033821002831



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Cancer Cell 40:835-849.e8(2022)



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