产品名称 |
BALL-1人B淋巴细胞急性白血病细胞 |
货号 |
ZQ0728 |
产品介绍 |
BALL-1是一种人B淋巴细胞急性白血病细胞系,它来源于1976年一名75岁男性急性人B淋巴细胞白血病病人的外周血。由于患者年龄较大,为老年人群中的疾病提供了独特的视角。 BALL-1 细胞表现出 B 细胞谱系的特征,特别是表达 CD19 和 CD10 等标记物。这些细胞表面免疫球蛋白呈阴性,与 B 细胞肿瘤发展早期观察到的表型一致。
BALL-1 对于研究 B 细胞白血病的发病机制至关重要,特别是在老年患者中,其疾病动态可能与在年轻个体中观察到的显着不同。该细胞系有助于探索白血病进展、治疗耐药和新药物靶点出现的分子和细胞机制。 BALL-1 在药物发现和测试方面发挥着重要作用,有助于评估新的抗白血病化合物。此外,BALL-1 中存在的遗传异常为 B 细胞前体急性淋巴细胞白血病发病机制中涉及的染色体改变提供了重要的见解。 |
种属 |
人 |
性别/年龄 |
男性/75岁 |
组织 |
外周血 |
疾病 |
成人B急性淋巴细胞白血病 |
细胞类型 |
肿瘤细胞 |
形态学 |
淋巴细胞样 |
生长方式 |
悬浮 |
倍增时间 |
大约48~80小时 |
培养基和添加剂 |
RPMI-1640(品牌:中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
ZM0728 |
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin:XY CSF1PO:10,12 D13S317:9,12 D16S539:9 D18S51:12,13 D19S433:13,15.2 D21S11:30 D2S1338:19,22 D3S1358:16 D5S818:10,13 D7S820:10,12 D8S1179:10,14 FGA:22,23 TH01:7,9 THOX:8,11 vWA:14,18; |
培养条件 |
95%空气,5%二氧化碳;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
DSMZ; ACC-742 JCRB; JCRB0071 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0728 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
原文链接: https://www.hindawi.com/journals/abb/2022/9708829/
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