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U251人神经胶质瘤细胞(STR鉴定)
英文名:U251
货号:ZQ0053
价格:¥1200.00
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U251人神经胶质瘤细胞(STR鉴定)

¥1200.00
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U251人胶质瘤细胞专用培养基

¥350.00 ¥450.00

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¥1550 ¥1650.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

U251人神经胶质瘤细胞

货号

ZQ0053

产品介绍

U251是一种人神经胶质瘤细胞系,源自一位75岁男性患者的胶质母细胞瘤组织。胶质母细胞瘤是一种常见的、恶性程度很高的原发性脑肿瘤,通常发生在星形胶质细胞中。U251在神经胶质瘤的研究中非常重要,它们具有快速的体外增殖能力、高度的侵袭性,并且携带多种与肿瘤发生和发展相关的基因突变,如TP53和EGFR突变。是神经胶质瘤研究的重要工具,它尽管存在局限性,但通过结合多种研究方法和技术,科学家们可以进一步揭示神经胶质瘤的生物学机制,并开发出更有效的治疗策略。

种属

性别/年龄

男/75岁

组织

脑组织

疾病

大脑顶叶;疾病:星形胶质细胞瘤(III-IV级)

细胞类型

肿瘤细胞

形态学

成纤维细胞样,多形型,

生长方式

贴壁

倍增时间

~24小时 

培养基和添加剂

DMEM高糖(品牌:中乔新舟 货号:ZQ-100)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006

推荐完全培养基货号

ZM0053

生物安全等级

BSL-1

STR位点信息

Amelogenin: X;
D5S818: 11,12;
D13S317: 10,11;
D7S820: 10,12;
D16S539: 12;
vWA: 16,18;
TH01: 9.3;
TPOX: 8;
CSF1PO: 11,12;
D19S433: 13,15;
D21S11: 29;
D18S51: 13;
D6S1043: 12;
D3S1358:16,17;
D16S539: 12;
D2S441: 11;
D8S1179: 13,15;
Penta E: 7,10;
D12S391: 17,22
D2S1338: 22,24;
FGA: 21,25;

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ECACC; 09063001

供应限制

仅供科研使用

货号

ZQ0053

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71
DOI: 10.3390/v13050774
发表时间: 2021-04-27
期刊: Viruses-Basel
影响因子: 5.048
货号: ZQ0053
产品名称: human astrocytes U251 MG cells

原文链接: https://www.mdpi.com/1089476


论文标题: Cyclic arginine-glycine-aspartic acid-modified red blood cells for drug delivery: synthesis and in vitro evaluation
DOI: 10.1016/j.jpha.2021.06.003
发表时间: 2021-06-12
期刊: Journal of Pharmaceutical Analysis
影响因子: 4.769
货号: ZQ0053
产品名称: U251 glioma cells
原文链接: https://www.sciencedirect.com/science/article/pii/S2095177921000630



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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)


PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)


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Mestdagh P., Lefever S., Volders P.-J., Derveaux S., Hellemans J., Vandesompele J.
Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR.
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Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)


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Allen M., Bjerke M., Edlund H., Nelander S., Westermark B.
Origin of the U87MG glioma cell line: good news and bad news.
Sci. Transl. Med. 8:354re3.1-354re3.4(2016)


PubMed=27807467; DOI=10.1186/s13100-016-0078-4; PMCID=PMC5087121
Zampella J.G., Rodic N., Yang W.R., Huang C.R.L., Welch J., Gnanakkan V.P., Cornish T.C., Boeke J.D., Burns K.H.
A map of mobile DNA insertions in the NCI-60 human cancer cell panel.
Mob. DNA 7:20.1-20.11(2016)


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Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)


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Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress.
BMC Cancer 18:496.1-496.19(2018)


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Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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PubMed=30971826; DOI=10.1038/s41586-019-1103-9
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Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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