产品名称	Raji人Burkitts淋巴瘤细胞
货号	ZQ0084
产品介绍	Raji是一种人Burkitt's淋巴瘤细胞系，最初由R.J.V. Pulvertaft于1963年从一名11岁黑人男性左上颌骨Burkitt淋巴瘤中建立。Raji细胞系在免疫学研究中目前在：CAR-T细胞治疗研究、NK细胞免疫杀伤研究、B细胞信号传导研究、EBV相关研究、免疫逃逸机制研究、药物代谢动力学研究等得到应用。这些应用展示了Raji细胞系在免疫学研究中的多样性和重要性，它们为理解B细胞淋巴瘤的复杂性提供了宝贵的工具。 EBNA阳性。 注意事项： （1）Raji细胞通常在悬浮中以不同大小的浮动簇生长。随着培养密度的增加，细胞簇可以变得非常大，尽管也可能存在一些单细胞。在这 个细胞系中，碎片是正常的。 （2）细胞浓度不应超过2-3 × 10^6个细胞/ml，应加入足够的培养基使细胞浓度降至3-5 × 10^5个活细胞/ml，并避免生长培养基过度酸化。
种属	人
性别/年龄	男/11岁
组织	淋巴母细胞
疾病	Burkitt淋巴瘤，EBV相关伯基特淋巴瘤(NCIt:C27694)，伯基特淋巴瘤(ORDO:Orphanet_543)。
细胞类型	肿瘤细胞
形态学	淋巴母细胞
生长方式	悬浮
倍增时间	大约20~36小时
培养基和添加剂	RPMI-1640（中乔新舟 货号：ZQ-200）+10%胎牛血清（中乔新舟 货号：ZQ0500）+1%双抗（中乔新舟   货号：CSP006）
推荐完全培养基货号	ZM0084
生物安全等级	BSL-2
STR位点信息	Amelogenin: X,Y D3S1358: 15,16 TH01: 6,7 D21S11: 28,31 D18S51: 17 Penta_E: 5,13 D5S818: 10,13 D13S317: 13 D7S820: 10 D16S539: 8,11 CSF1PO: 10,12 Penta_D: 3.2,9 vWA: 16,19 D8S1179: 14,15 TPOX: 8,13 FGA: 19,27 D19S433: 14,14.2 D2S1338: 22
培养条件	95%空气，5%二氧化碳；37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC; CCL-86 ATCC; CRL-7936 DSMZ; ACC-319 ECACC; 85011429
供应限制	仅供科研使用

货号	ZQ0084
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

1、论文标题： Conditional control of chimeric antigen receptor T-cell activity through a destabilizing domain switch and its chemical ligand
DOI： 10.1016/j.jcyt.2021.07.014
发表时间： 2021-09-28
期刊： CYTOTHERAPY
影响因子： 5.414
货号： ZQ0084
产品名称： Raji cells

原文链接： https://www.sciencedirect.com/science/article/pii/S1465324921007489

2、论文标题： Preparation and evaluation of etoposide-loaded lipid-based nanosuspensions for high-dose treatment of lymphoma
DOI： 10.2217/nnm-2018-0502
发表时间： 2019-06-10
期刊： Nanomedicine
影响因子： 4.717
货号： ZQ0084
产品名称： Human Raji lymphoma cells
原文链接： https://www.futuremedicine.com/doi/abs/10.2217/nnm-2018-0334

3、论文标题： Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway
DOI： 10.3892/mmr.2020.11785
发表时间： 2020-12-15
期刊： Molecular Medicine Reports
影响因子： 2.1
货号： ZQ0084
产品名称： Raji cells
原文链接： https://www.spandidos-publications.com/10.3892/mmr.2020.11785

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